USP15 is a deubiquitylating enzyme for receptor-activated SMADs
about
USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastomaFine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitinationKey role for ubiquitin protein modification in TGFβ signal transductionRegulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsRegulation of TGF-β Superfamily Signaling by SMAD Mono-UbiquitinationCullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signalingNAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathwayTGFβ signalling in contextOver-expression of deubiquitinating enzyme USP14 in lung adenocarcinoma promotes proliferation through the accumulation of β-cateninUSP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination.USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31.USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responsesUSP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability.The regulation of TGF-β/SMAD signaling by protein deubiquitination.Deubiquitylation of deubiquitylasesThe self-limiting dynamics of TGF-β signaling in silico and in vitro, with negative feedback through PPM1A upregulation.RNA profiles of porcine embryos during genome activation reveal complex metabolic switch sensitive to in vitro conditions.Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancerNon-degradative ubiquitination in Smad-dependent TGF-β signalingAerobic glycolysis tunes YAP/TAZ transcriptional activityDeubiquitinases in cancer.USP11 augments TGFβ signalling by deubiquitylating ALK5.Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms.Protein monoubiquitylation: targets and diverse functionsDefining the Microglia Response during the Time Course of Chronic NeurodegenerationThe deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exitTargeting ubiquitination for cancer therapies.The WD40-repeat protein-containing deubiquitinase complex: catalysis, regulation, and potential for therapeutic intervention.Deubiquitylation of hepatitis B virus X protein (HBx) by ubiquitin-specific peptidase 15 (USP15) increases HBx stability and its transactivation activity.De-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II.SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblastsThe Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases.Genome-wide mechanisms of Smad binding.Post-translational regulation of TGF-β receptor and Smad signaling.Regulation of the transforming growth factor β pathway by reversible ubiquitylation.New insights into extracellular and post-translational regulation of TGF-β family signalling pathways.The TGFbeta superfamily signaling pathway.
P2860
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P248
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P2860
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@ast
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en-gb
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@nl
type
label
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@ast
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en-gb
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@nl
prefLabel
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@ast
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en-gb
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
@en
P2093
Andrea Manfrin
Leonardo Morsut
Sandra Soligo
Simona Polo
Stefano Piccolo
P2860
P2888
P304
P3181
P356
10.1038/NCB2346
P407
P50
P577
2011-11-01T00:00:00Z
P5875
P6179
1007059878