about
LncRNA HOTAIR: A master regulator of chromatin dynamics and cancerLarge intervening non-coding RNA HOTAIR is an indicator of poor prognosis and a therapeutic target in human cancersFunctions of lncRNA HOTAIR in lung cancerKeeping abreast with long non-coding RNAs in mammary gland development and breast cancerLong non-coding RNA HOTAIR in carcinogenesis and metastasisRegulation of mammary epithelial cell homeostasis by lncRNAsHistones and their modifications in ovarian cancer - drivers of disease and therapeutic targets.A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.Regulation and Role of EZH2 in CancerThe methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancersThe role of non-coding RNAs in the regulation of stem cells and progenitors in the normal mammary gland and in breast tumors.Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants.FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.Androgens regulate SMAD ubiquitination regulatory factor-1 expression and prostate cancer cell invasionLncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer.Inhibition of EZH2 by chemo- and radiotherapy agents and small molecule inhibitors induces cell death in castration-resistant prostate cancerBRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancerNoncoding RNAs in breast cancer.Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution.Long non-coding RNAs and their implications in cancer epigenetics.Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis.Inhibiting histone deacetylases suppresses glucose metabolism and hepatocellular carcinoma growth by restoring FBP1 expression.CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy.Roles of enhancer of zeste homolog 2: from skeletal muscle differentiation to rhabdomyosarcoma carcinogenesis.Long noncoding RNA HOTAIR involvement in cancer.Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer.lincRNA HOTAIR as a novel promoter of cancer progression.Long noncoding RNAs: a potential novel class of cancer biomarkers.Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.Non-coding RNAs in Mammary Gland Development and Disease.A brief review on long noncoding RNAs: a new paradigm in breast cancer pathogenesis, diagnosis and therapy.AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction.MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation.Specific long non-coding RNAs response to occupational PAHs exposure in coke oven workers.Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer.EZH2 takes the stage when BRCA1 losesEZH2 and histone deacetylase inhibitors induce apoptosis in triple negative breast cancer cells by differentially increasing H3 Lys27 acetylation in the BIM gene promoter and enhancers.Long Noncoding RNA HOTAIR Modulates MiR-206-mediated Bcl-w Signaling to Facilitate Cell Proliferation in Breast Cancer.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
BRCA1 is a negative modulator of the PRC2 complex
@ast
BRCA1 is a negative modulator of the PRC2 complex
@en
BRCA1 is a negative modulator of the PRC2 complex
@en-gb
BRCA1 is a negative modulator of the PRC2 complex
@nl
type
label
BRCA1 is a negative modulator of the PRC2 complex
@ast
BRCA1 is a negative modulator of the PRC2 complex
@en
BRCA1 is a negative modulator of the PRC2 complex
@en-gb
BRCA1 is a negative modulator of the PRC2 complex
@nl
prefLabel
BRCA1 is a negative modulator of the PRC2 complex
@ast
BRCA1 is a negative modulator of the PRC2 complex
@en
BRCA1 is a negative modulator of the PRC2 complex
@en-gb
BRCA1 is a negative modulator of the PRC2 complex
@nl
P2093
P2860
P3181
P356
P1433
P1476
BRCA1 is a negative modulator of the PRC2 complex
@en
P2093
Aaron Sarver
Antonius Koller
Haojie Huang
Jonathan C Zhao
Junjie Chen
Liguo Wang
P2860
P304
P3181
P356
10.1038/EMBOJ.2013.95
P407
P50
P577
2013-04-26T00:00:00Z