The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers - Test2 - elhamkhani - TriplyDB

The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers

The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers

http://www.wikidata.org/entity/Q34861658

about

Polycomb repressive complex's evolutionary conserved function: the role of EZH2 status and cellular background Prognostic value of high EZH2 expression in patients with different types of cancer: a systematic review with meta-analysis Hidden among the crowd: differential DNA methylation-expression correlations in cancer occur at important oncogenic pathways Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis High EZH2 Protein Expression Is Associated with Poor Overall Survival in Patients with Luminal A Breast Cancer The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer.Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer.Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors.Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.The role of EZH2 in overall survival of colorectal cancer: a meta-analysis.Association of clinicopathologic characteristics and outcomes with EZH2 expression in patients with breast cancer in East Azerbaijan, Iran.EZH2-mediated suppression of lncRNA-LET promotes cell apoptosis and inhibits the proliferation of post-burn skin fibroblasts.miR-17-5p down-regulation contributes to erlotinib resistance in non-small cell lung cancer cells.Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids

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P2860

The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers

http://www.wikidata.org/entity/Q34861658

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

The methyltransferase EZH2 is ...... of ER-positive breast cancers

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The methyltransferase EZH2 is ...... of ER-positive breast cancers

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The methyltransferase EZH2 is ...... of ER-positive breast cancers

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The methyltransferase EZH2 is ...... of ER-positive breast cancers

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The methyltransferase EZH2 is ...... of ER-positive breast cancers

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Molecular Carcinogenesis

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The methyltransferase EZH2 is ...... of ER-positive breast cancers

@en

P2093

Ik-Joo Chung

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Ji Shin Lee

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Jung Han Yoon

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Kyung Hyun Yoo

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Min Ho Park

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Priscilla A Furth

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Woo Kyun Bae

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Young Kim

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P2860

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

BRCA1 is a negative modulator of the PRC2 complex

Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Chromatin modifications and their function

The histone demethylase UTX enables RB-dependent cell fate control

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Molecular classification of tamoxifen-resistant breast carcinomas by gene expression profiling.

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1172-1180

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scholarly article

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10.1002/MC.22188

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10

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54

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Lothar Hennighausen

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2014-07-07T00:00:00Z

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25043748

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4286524

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