The human CST complex is a terminator of telomerase activity
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityHOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmentTelomere- and Telomerase-Associated Proteins and Their Functions in the Plant CellStructure and function of the telomeric CST complexShort telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancyTelomeres-structure, function, and regulationStructure of the Human Telomeric Stn1-Ten1 Capping ComplexA three-state model for the regulation of telomerase by TERRA and hnRNPA1The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIsThe telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structuresZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activatorHuman telomerase: biogenesis, trafficking, recruitment, and activation.The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response.MERISTEM DISORGANIZATION1 encodes TEN1, an essential telomere protein that modulates telomerase processivity in Arabidopsis.Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres.Transcriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptideTelomere biology and translational research.CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance.CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosisTelomere Biology-Insights into an Intriguing Phenomenon.Coordination of transposon expression with DNA replication in the targeting of telomeric retrotransposons in Drosophila.Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implicationsSUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.Human CST has independent functions during telomere duplex replication and C-strand fill-inStructure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactionsGene expression levels of human shelterin complex and shelterin-associated factors regulated by the topoisomerase II inhibitors doxorubicin and etoposide in human cultured cells.Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase.Unraveling secrets of telomeres: one molecule at a time.Human leukocyte telomere length is associated with DNA methylation levels in multiple subtelomeric and imprinted lociTpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association.Role of STN1 and DNA polymerase α in telomere stability and genome-wide replication in Arabidopsis.POT1a and components of CST engage telomerase and regulate its activity in Arabidopsis.Stn1 is critical for telomere maintenance and long-term viability of somatic human cells.Evolution of the Telomere-Associated Protein POT1a in Arabidopsis thaliana Is Characterized by Positive Selection to Reinforce Protein-Protein InteractionDownregulation of telomerase maintenance-related ACD expression in patients undergoing immunosuppresive therapy following kidney transplantationA POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plusTelomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis.Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres.STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function.
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The human CST complex is a terminator of telomerase activity
description
2012 nî lūn-bûn
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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
The human CST complex is a terminator of telomerase activity
@ast
The human CST complex is a terminator of telomerase activity
@en
The human CST complex is a terminator of telomerase activity
@en-gb
The human CST complex is a terminator of telomerase activity
@nl
type
label
The human CST complex is a terminator of telomerase activity
@ast
The human CST complex is a terminator of telomerase activity
@en
The human CST complex is a terminator of telomerase activity
@en-gb
The human CST complex is a terminator of telomerase activity
@nl
prefLabel
The human CST complex is a terminator of telomerase activity
@ast
The human CST complex is a terminator of telomerase activity
@en
The human CST complex is a terminator of telomerase activity
@en-gb
The human CST complex is a terminator of telomerase activity
@nl
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The human CST complex is a terminator of telomerase activity
@en
P2093
Sophie Redon
P2888
P304
P3181
P356
10.1038/NATURE11269
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P577
2012-08-01T00:00:00Z
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1009928416