The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
about
In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAsA mammalian factor that binds telomeric TTAGGG repeats in vitroHuman POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.POT1 association with TRF2 regulates telomere lengthMinimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitroControl of human telomere length by TRF1 and TRF2Extensive telomere repeat arrays in mouse are hypervariableTelomere elongation in immortal human cells without detectable telomerase activityHuman telomerase contains evolutionarily conserved catalytic and structural subunitsFunctional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationCiliate telomerase RNA structural featuresIdentification of a novel nuclear domainBRCA1 inhibition of telomerase activity in cultured cellsCritical evaluation of urinary markers for bladder cancer detection and monitoringTelomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenitaInvolvement of 14-3-3 proteins in nuclear localization of telomeraseIs telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer?hTERT protein expression is independent of clinicopathological parameters and c-Myc protein expression in human breast cancerTelomerase: The Devil InsideRoles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesTelomere and Telomerase Therapeutics in CancerTelomerase reverse transcriptase moonlights: Therapeutic targets beyond telomeraseIt all comes together at the ends: telomerase structure, function, and biogenesisPotential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactoneThe role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesTherapeutic targeting of replicative immortalityThe high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkagesThe yeast Pif1p helicase removes telomerase from telomeric DNA.TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeresInvolvement of the silencer and UAS binding protein RAP1 in regulation of telomere length.Understanding specific functions of PARP-2: new lessons for cancer therapyTelomerase activity and telomere length in male germ cellsFunctional requirement of p23 and Hsp90 in telomerase complexesAn anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalizationSwitching human telomerase on and off with hPOT1 protein in vitroInTERTesting association between telomerase, mTOR and phytochemicalsThe RNA component of human telomeraseStructure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protectionGenetic variation in telomere maintenance genes, telomere length and breast cancer riskHuman telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo
P2860
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P2860
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
description
1989 nî lūn-bûn
@nan
1989 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@ast
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en-gb
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@nl
type
label
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@ast
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en-gb
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@nl
prefLabel
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@ast
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en-gb
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@nl
P921
P3181
P1433
P1476
The human telomere terminal tr ...... hat synthesizes TTAGGG repeats
@en
P2093
P3181
P356
10.1016/0092-8674(89)90035-4
P407
P577
1989-11-03T00:00:00Z