It all comes together at the ends: telomerase structure, function, and biogenesis - Test2 - elhamkhani - TriplyDB

It all comes together at the ends: telomerase structure, function, and biogenesis

It all comes together at the ends: telomerase structure, function, and biogenesis

http://www.wikidata.org/entity/Q26823394

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The telomere syndromes Therapeutic Targeting of Telomerase Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases Telomerase and idiopathic pulmonary fibrosis Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy Therapeutic targeting of replicative immortality Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65 Active Yeast Telomerase Shares Subunits with Ribonucleoproteins RNase P and RNase MRP The Telomere/Telomerase System in Chronic Inflammatory Diseases. Cause or Effect?Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer The functional requirement of two structural domains within telomerase RNA emerged early in eukaryotes Many disease-associated variants of hTERT retain high telomerase enzymatic activity Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT.Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.A self-regulating template in human telomerase.The telomerase reverse transcriptase subunit from the dimorphic fungus Ustilago maydis.Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA.Baculovirus vector-mediated transfer of sodium iodide symporter and plasminogen kringle 5 genes for tumor radioiodide therapy.The Relationship between Telomerase Activity and Clinicopathological Parameters in Colorectal Cancer: A Meta-Analysis.Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle.Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes.Biogenesis of telomerase ribonucleoproteins Structure and function of echinoderm telomerase RNA.Control of telomerase action at human telomeres Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation A trans-spliced telomerase RNA dictates telomere synthesis in Trypanosoma brucei A homozygous telomerase T-motif variant resulting in markedly reduced repeat addition processivity in siblings with Hoyeraal Hreidarsson syndrome.Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach Evolutionary perspectives of telomerase RNA structure and function.Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.xRRM: a new class of RRM found in the telomerase La family protein p65.Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres.TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.Shorter telomeres and high telomerase activity correlate with a highly aggressive phenotype in breast cancer cell lines.A combination of the telomerase inhibitor, BIBR1532, and paclitaxel synergistically inhibit cell proliferation in breast cancer cell lines.Effect of targeted silencing of hTERT mRNA by lentivirus-mediated siRNA on A549 lung cancer cells in vitro.

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P2860

It all comes together at the ends: telomerase structure, function, and biogenesis

http://www.wikidata.org/entity/Q26823394

description

2012 nî lūn-bûn

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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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It all comes together at the ends: telomerase structure, function, and biogenesis

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J.MRFMMM.2011.11.002

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Mutation Research

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It all comes together at the ends: telomerase structure, function, and biogenesis

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Joshua D. Podlevsky

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Julian J.-L. Chen

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P2860

A telomerase component is defective in the human disease dyskeratosis congenita

Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

Cell cycle-regulated trafficking of human telomerase to telomeres

X-linked dyskeratosis congenita is predominantly caused by missense mutations in the DKC1 gene.

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10.1016/J.MRFMMM.2011.11.002

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2012-02-01T00:00:00Z

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22093366

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4420735

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