Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts - Test2 - elhamkhani - TriplyDB

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

http://www.wikidata.org/entity/Q24532054

about

A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions Vitamin D receptor agonists: suitable candidates as novel therapeutic options in autoimmune inflammatory myopathy Wdr68 requires nuclear access for craniofacial development Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition Examination of the expanding pathways for the regulation of p21 expression and activity.Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species.The kinase Mirk is a potential therapeutic target in osteosarcoma.The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species Depleting Mirk Kinase Increases Cisplatin Toxicity in Ovarian Cancer Cells.Cell death-resistance of differentiated myotubes is associated with enhanced anti-apoptotic mechanisms compared to myoblasts.The role of mirk kinase in sarcomas KAT5-mediated SOX4 acetylation orchestrates chromatin remodeling during myoblast differentiation New targets to treat obesity and the metabolic syndrome.IRES-mediated translation of the pro-apoptotic Bcl2 family member PUMA.The Kinase Mirk/dyrk1B: A Possible Therapeutic Target in Pancreatic Cancer The C-terminal region of E1A: a molecular tool for cellular cartography.Less understood issues: p21(Cip1) in mitosis and its therapeutic potential.The RNA-binding protein CUGBP1 regulates stability of tumor necrosis factor mRNA in muscle cells: implications for myotonic dystrophy.Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1b and p130/RB2.Down-regulation of CIBZ, a novel substrate of caspase-3, induces apoptosis.Mirk/dyrk1B Kinase in Ovarian Cancer.The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling.Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.Signaling through the TRAIL receptor DR5/FADD pathway plays a role in the apoptosis associated with skeletal myoblast differentiation.Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr(286), not Thr(288).Binding of calmodulin to the carboxy-terminal region of p21 induces nuclear accumulation via inhibition of protein kinase C-mediated phosphorylation of Ser153.Dietary resveratrol confers apoptotic resistance to oxidative stress in myoblasts.Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells.Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.

P2860

Q21284144-6C2EF5B7-64FC-4A6D-A2C2-6AB5B009BF05 Q24302518-36AD5EED-A170-4EA5-8D9A-C2CC83B36392 Q24319987-864168D6-346E-4834-B457-25C6E4648ECB Q26849424-DF4692F1-4AEE-468A-A522-44A88E1C5494 Q27319944-69B8E08F-55A4-444F-8B68-62A061ACAF8B Q27678087-CD58126C-1CFF-446F-AABA-718BC06ACE19 Q27692024-C03F8008-94D1-4828-9708-3328159B1BBD Q28541616-DB243B0F-06D9-4BC8-9FA5-080FC8CC5383 Q33242077-56D8BE4E-D17F-4B81-878D-95892E71F94E Q33427731-842BE022-45B4-4001-AAAF-DF28C4A16053 Q33521423-11EE37E4-8C31-4C22-A35E-7D11B60C1CCC Q33776829-E867DF9A-ECD2-4951-902A-1394068DEFFD Q34339955-13F31A2A-D68E-424A-922F-DBE7E1DC5176 Q34609532-B6FE1D8E-3F22-488D-A5CB-C27A76A48D7F Q34928886-26D352DA-845D-4BDF-826F-3946C1EFE11A Q36022225-FD144187-38C6-4F71-A802-61CB978AFF3D Q36068914-ECDE7FDF-66FF-4628-B51D-E8A3CFCC9A86 Q36477557-F8C2D7FF-116B-4186-A7C0-F2E944DB5C59 Q37334250-84612467-CAB6-4AEC-80D4-53F5D51C18AF Q37980172-7C1BD3C8-CB25-41DE-8039-6BD068EA8FA5 Q38214413-D0381C56-3504-495B-ABAC-A51A84250485 Q38290011-913F6534-5473-4FDF-A5D7-DFE86C6E0BD4 Q39653282-BB85FBE0-0E69-473E-827F-09B870C828DD Q39997162-AB7C1538-3F14-4EC7-A10B-CA5BC0741656 Q40044634-F4595562-2A30-4922-92C8-B05CDB88C0AE Q40356655-EC943776-4790-4321-89C7-27809075EDD2 Q41782221-D3D8F8A9-BFD2-4190-98B7-62B45C3C3CA0 Q42242386-4EB21B5C-6EAB-42A1-B483-0EBDDB3D8D5E Q42360652-6AB79885-CAF6-4684-B823-D889679BBC09 Q42708880-CC764A56-3A8D-4EF6-9117-B287E8AD2598 Q42811646-E2AF2833-7115-4764-985F-F07758E67DAB Q45070601-2B3675BD-B378-4E89-ACC5-446E5769D929 Q47654334-8C2058D4-0778-410B-9BE0-6E7AA782E146 Q52641599-6ED2F923-6B72-4378-9042-593F36A57781 Q54117942-6B1C9B2B-4DC6-44AD-8188-B45653800BA2

P2860

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

http://www.wikidata.org/entity/Q24532054

description

2005 nî lūn-bûn

@nan

2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

name

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@ast

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en-gb

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@nl

type

label

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@ast

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en-gb

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@nl

prefLabel

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@ast

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en-gb

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@nl

P1433

Q24532054-7AB05626-9378-46B3-97A8-207BBC4C338B

P1476

Q24532054-58D57F5D-8131-4B0A-B639-2DE76694BAC7

P2093

Q24532054-3BA0D95B-2D17-4E88-9C9B-61CE3DE7C6E5

Q24532054-6BD7B4DC-5DCF-45C5-9A63-18EFF8EFF848

Q24532054-6CBABFCA-1ABA-4D4B-8570-A560B1B8966A

Q24532054-9D1B7AD8-A77A-4E28-9042-5AC90C943A66

Q24532054-C3056ECF-0E5D-4A18-9A50-C0CC28360182

Q24532054-CD5BBCBB-DC59-4E9B-A1F8-3A6042FE8B86

P2860

Q24532054-00F74522-6A17-43F1-BB0D-0DC6CE5BA6A7

Q24532054-05CA50C4-73D9-4033-9D36-12F11C9F931C

Q24532054-09B0ADE8-EBF5-4F35-926F-019445CB76C5

Q24532054-0BA1BABF-8BB2-4329-B3BE-0C60D7B5BED0

Q24532054-0DF4AC4A-9711-49B3-8FDA-52330C0792B2

Q24532054-119D3489-DF59-4FBF-BBFC-BA0301D3E0DB

Q24532054-1205509B-781B-41B1-A5AC-EBAA92931242

Q24532054-12C1246E-F847-40E0-873A-A24E79D1E554

Q24532054-14E6BF39-3898-4174-A738-FD5B434A84FE

Q24532054-15FB55CC-6F83-44EA-A6FC-A9F11D7F977A

P304

Q24532054-B9F2D09E-09A9-449B-8EC3-7CA6BCCD161A

P31

Q24532054-DC9DD656-577B-4F48-AD62-0C148BD2D80D

P356

Q24532054-BF295219-4E9A-423C-93D8-903771519212

P407

Q24532054-0A3CE535-CD2F-4B27-B1B5-BC00FBED785A

P433

Q24532054-BB22F65A-92E4-4776-9384-B1DF771620ED

P478

Q24532054-DA67A045-F3DD-48FA-8513-53512572DFC9

P577

Q24532054-A443151F-2294-4299-B173-ED4AD7BEE436

P5875

Q24532054-0D308B6F-82F6-4F8D-8439-58645F34D9A8

P698

Q24532054-400A7414-D1FF-44FD-92A3-2CE8B750D0FA

P921

Q24532054-72601544-B558-4457-B4C9-437142E28673

Q24532054-FADA174F-9774-408B-933E-F3F306B0F927

P932

Q24532054-C42BA445-53A9-4C73-B131-0961196C3BC0

P356

P1433

Journal of Biological Chemistry

P1476

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

@en

P2093

Daina Z Ewton

http://www.w3.org/2001/XMLSchema#string

Eileen Friedman

http://www.w3.org/2001/XMLSchema#string

Seunghwan Lim

http://www.w3.org/2001/XMLSchema#string

Stephen E Mercer

http://www.w3.org/2001/XMLSchema#string

Thomas R Mazur

http://www.w3.org/2001/XMLSchema#string

Xiaobing Deng

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of the MEF2 family of transcription factors by p38

Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors

Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha

New functional activities for the p21 family of CDK inhibitors

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps

WAF1, a potential mediator of p53 tumor suppression

Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal.

P304

25788-25801

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M413594200

http://www.w3.org/2001/XMLSchema#string

P407

P433

27

http://www.w3.org/2001/XMLSchema#string

P478

280

http://www.w3.org/2001/XMLSchema#string

P577

2005-04-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7887360

http://www.w3.org/2001/XMLSchema#string

P698

15851482

http://www.w3.org/2001/XMLSchema#string

P921

P932

1201501

http://www.w3.org/2001/XMLSchema#string