Signal-dependent membrane targeting by pleckstrin homology (PH) domains
about
Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificitiesCharacterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the GolgiEvidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivoMechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domainsKindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrinsInteraction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1Association of Grb7 with phosphoinositides and its role in the regulation of cell migrationNon-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptorLL5beta directs the translocation of filamin A and SHIP2 to sites of phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3) accumulation, and PtdIns(3,4,5)P3 localization is mutually modified by co-recruited SHIP2.Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functionsAn alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingMal connects TLR2 to PI3Kinase activation and phagocyte polarizationPtdIns(4,5)P-restricted plasma membrane localization of FAN is involved in TNF-induced actin reorganizationHuman junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P3 and the S101R mutation identified in hypertrophic cardiomyopathy obviates this responseThe oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartmentsThe cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerizationPTEN function: how normal cells control it and tumour cells lose itThe plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domainExo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEFPlacental overgrowth in mice lacking the imprinted gene IplCellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteinsCrystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificityThe Phox homology (PX) domain, a new player in phosphoinositide signallingPKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.High-affinity interaction of the N-terminal myristoylation motif of the neuronal calcium sensor protein hippocalcin with phosphatidylinositol 4,5-bisphosphateCritical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformationMolecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase.The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinctDiacylglycerol kinase delta suppresses ER-to-Golgi traffic via its SAM and PH domainsPhylogenetic analysis of Sec7-domain-containing Arf nucleotide exchangersDock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complexStructural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1Function of the N-terminus of zizimin1: autoinhibition and membrane targeting.Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformationPI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.SYNGAP1: Mind the GapBivalent inhibitors of protein kinasesThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migration
P2860
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P2860
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@ast
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en-gb
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@nl
type
label
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@ast
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en-gb
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@nl
prefLabel
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@ast
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en-gb
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@nl
P2860
P3181
P1433
P1476
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
@en
P2093
K M Ferguson
P2860
P3181
P356
10.1042/0264-6021:3500001
10.1042/BJ3500001
P407
P478
P577
2000-08-01T00:00:00Z