Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation.
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Identification and characterization of gamma-glutamylamine cyclotransferase, an enzyme responsible for gamma-glutamyl-epsilon-lysine catabolismThe identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycleStructures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor bindingKinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthusStructure of glutaminyl cyclase fromDrosophila melanogasterin space groupI4Structural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor bindingIdentification of Glutaminyl Cyclase Genes Involved in Pyroglutamate Modification of Fungal Lignocellulolytic EnzymesSoluble variants of human recombinant glutaminyl cyclaseLinked production of pyroglutamate-modified proteins via self-cleavage of fusion tags with TEV protease and autonomous N-terminal cyclization with glutaminyl cyclase in vivoInterrogating the Venom of the Viperid Snake Sistrurus catenatus edwardsii by a Combined Approach of Electrospray and MALDI Mass SpectrometryGlutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution.Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions.An artifact in LC-MS/MS measurement of glutamine and glutamic acid: in-source cyclization to pyroglutamic acid.Novel insights in the use of hydrolytic enzymes secreted by fungi with biotechnological potential.siRNA screen identifies QPCT as a druggable target for Huntington's disease.Stability, permeability and growth-inhibitory properties of gonadotropin-releasing hormone liposaccharides.Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity.The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease.Papaya glutamine cyclotransferase shows a singular five-fold beta-propeller architecture that suggests a novel reaction mechanism.Alteration of oligomeric state and domain architecture is essential for functional transformation between transferase and hydrolase with the same scaffold.Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics.Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.Microheterogeneity of Recombinant Antibodies: Analytics and Functional Impact.A phase 1 study to evaluate the safety and pharmacokinetics of PQ912, a glutaminyl cyclase inhibitor, in healthy subjects.
P2860
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P2860
Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Crystal structures of human gl ...... rminal pyroglutamate formation
@nl
Crystal structures of human gl ...... minal pyroglutamate formation.
@ast
Crystal structures of human gl ...... minal pyroglutamate formation.
@en
Crystal structures of human gl ...... minal pyroglutamate formation.
@en-gb
type
label
Crystal structures of human gl ...... rminal pyroglutamate formation
@nl
Crystal structures of human gl ...... minal pyroglutamate formation.
@ast
Crystal structures of human gl ...... minal pyroglutamate formation.
@en
Crystal structures of human gl ...... minal pyroglutamate formation.
@en-gb
prefLabel
Crystal structures of human gl ...... rminal pyroglutamate formation
@nl
Crystal structures of human gl ...... minal pyroglutamate formation.
@ast
Crystal structures of human gl ...... minal pyroglutamate formation.
@en
Crystal structures of human gl ...... minal pyroglutamate formation.
@en-gb
P2093
P2860
P356
P1476
Crystal structures of human gl ...... minal pyroglutamate formation.
@en
P2093
Kai-Fa Huang
Wei-Ju Cheng
Yi-Liang Liu
P2860
P304
13117-13122
P356
10.1073/PNAS.0504184102
P407
P577
2005-08-31T00:00:00Z