The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70
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Mechanisms of CFTR Folding at the Endoplasmic ReticulumMolecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic FibrosisSmall intestinal mucosa expression of putative chaperone fls485Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperoneBAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorRegulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity.The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyDistinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast.CFTR Modulators: Shedding Light on Precision Medicine for Cystic FibrosisMutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type IAugmentation of CFTR maturation by S-nitrosoglutathione reductase.Deletion of CFTR translation start site reveals functional isoforms of the protein in CF patients.Diesel exhaust particles disturb gene expression in mouse testis.Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexinContribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity.Applications of proteomic technologies for understanding the premature proteolysis of CFTR.Cystic fibrosis transmembrane conductance regulator degradation: cross-talk between the ubiquitylation and SUMOylation pathways.Isoform specificity among ankyrins. An amphipathic alpha-helix in the divergent regulatory domain of ankyrin-b interacts with the molecular co-chaperone Hdj1/Hsp40.Pharmacological induction of the heat shock response improves myelination in a neuropathic modelRole of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation.Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms.4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cellsSmall heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation.Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels.Hallmarks of therapeutic management of the cystic fibrosis functional landscape.Combination of Correctors Rescue ΔF508-CFTR by Reducing Its Association with Hsp40 and Hsp27.COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit codeTherapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier-dependent pathway.HSP70 binding protein 1 (HspBP1) suppresses HIV-1 replication by inhibiting NF-κB mediated activation of viral gene expression.Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells.The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation).The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for unconventional protein secretion.Chemical and biological folding contribute to temperature-sensitive DeltaF508 CFTR traffickingAcute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms.Mis-trafficking of bicarbonate transporters: implications to human diseases.New drugs for cystic fibrosis.The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channels
P2860
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P2860
The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@ast
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en-gb
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@nl
type
label
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@ast
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en-gb
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@nl
prefLabel
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@ast
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en-gb
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@nl
P2860
P50
P921
P3181
P356
P1433
P1476
The human DnaJ homologue (Hdj) ...... conductance regulator by Hsp70
@en
P2860
P304
P3181
P356
10.1042/BJ20011717
P407
P577
2002-09-15T00:00:00Z