The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
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Mechanisms of CFTR Folding at the Endoplasmic ReticulumMolecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic FibrosisDeletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperoneThe human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channelsThe cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorMechanisms for regulation of Hsp70 function by Hsp40Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclatureHsp70 chaperones: cellular functions and molecular mechanismOne step at a time: endoplasmic reticulum-associated degradationAnatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins?Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity.Mechanisms for quality control of misfolded transmembrane proteinsThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyDissecting the ER-associated degradation of a misfolded polytopic membrane protein.Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing.Exchangeable chaperone modules contribute to specification of type I and type II Hsp40 cellular function.Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast.CFTR Modulators: Shedding Light on Precision Medicine for Cystic FibrosisThe cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutantsThe chaperone environment at the cytoplasmic face of the endoplasmic reticulum can modulate rhodopsin processing and inclusion formationA mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding proteinHuman DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domainBAG-6 is essential for selective elimination of defective proteasomal substratesThe endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508Augmentation of CFTR maturation by S-nitrosoglutathione reductase.HSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.Chaperone functions of the E3 ubiquitin ligase CHIP.Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator.Development of CFTR StructureActivation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione.The ΔF508-CFTR mutation inhibits wild-type CFTR processing and function when co-expressed in human airway epithelia and in mouse nasal mucosa.De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells.The role of the UPS in cystic fibrosis.Cystic fibrosis as a disease of misprocessing of the cystic fibrosis transmembrane conductance regulator glycoproteinInterplay between ER exit code and domain conformation in CFTR misprocessing and rescue.Hsp40 chaperones promote degradation of the HERG potassium channel.The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones.
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P2860
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@ast
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@en
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@nl
type
label
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@ast
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@en
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@nl
prefLabel
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@ast
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@en
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@nl
P2093
P2860
P3181
P356
P1433
P1476
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/18.6.1492
P407
P577
1999-03-15T00:00:00Z