Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells
about
Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic eraTRIM5 is an innate immune sensor for the retrovirus capsid latticeSpecific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factorHIV type 1 Gag as a target for antiviral therapyRestriction of retroviral replication by APOBEC3G/F and TRIM5alphaIndependent evolution of an antiviral TRIMCyp in rhesus macaquesTime-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living CellsCyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.Polymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infectionGene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent mannerLv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationRegulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS.Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses.Variants in host viral replication cycle genes are associated with heterosexual HIV-1 acquisition in AfricansHost genetics influences on HIV type-1 disease.The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins.Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction.The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicaseAdaptation of HIV-1 to cells expressing rhesus monkey TRIM5αIntracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogensArsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent mannerCyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cellsA novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screenHow TRIM5alpha defends against retroviral invasionsHomology-based identification of capsid determinants that protect HIV1 from human TRIM5α restrictionCyclosporine increases human immunodeficiency virus type 1 vector transduction of primary mouse cells.Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins.A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cellsRole of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infectionHost cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication.HIV Restriction Factors and Mechanisms of Evasion.Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 TransgeneAnalysis of human cell heterokaryons demonstrates that target cell restriction of cyclosporine-resistant human immunodeficiency virus type 1 mutants is genetically dominant.Identification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells.Dynamic allostery governs cyclophilin A-HIV capsid interplayBreaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives.
P2860
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P2860
Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@ast
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@en
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@nl
type
label
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@ast
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@en
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@nl
prefLabel
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@ast
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@en
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@nl
P2093
P2860
P3181
P356
P1476
Cyclophilin A is required for ...... IV-1 in Old World monkey cells
@en
P2093
Elena Sokolskaja
Lionel Berthoux
Sarah Sebastian
P2860
P304
P3181
P356
10.1073/PNAS.0505659102
P407
P50
P577
2005-10-11T00:00:00Z