Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor - Test2 - elhamkhani - TriplyDB

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

http://www.wikidata.org/entity/Q24547409

about

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions TRIM5 is an innate immune sensor for the retrovirus capsid lattice TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition TRIM5α and Species Tropism of HIV/SIV TRIM E3 ligases interfere with early and late stages of the retroviral life cycle Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein HIV type 1 Gag as a target for antiviral therapy Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha Independent evolution of an antiviral TRIMCyp in rhesus macaques All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function Impact of TRIM5α in vivo HIV-1 capsid: the multifaceted key player in HIV-1 infection Evolution of foamy viruses: the most ancient of all retroviruses Coupling viruses to dynein and kinesin-1 HIV-1 reverse transcription Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.Active site remodeling switches HIV specificity of antiretroviral TRIMCyp Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus Conformational Adaptation of Asian Macaque TRIMCyp Directs Lineage Specific Antiviral Activity Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein Structure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition module Structural insight into HIV-1 capsid recognition by rhesus TRIM5 Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity A unique spumavirus Gag N-terminal domain with functional properties of orthoretroviral matrix and capsid Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice Principles of Virus Uncoating: Cues and the Snooker Ball Immunologic manifestations of autophagy Optimal cytoplasmic transport in viral infections TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces Fates of retroviral core components during unrestricted and TRIM5-restricted infection Gene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent manner Fluorescent image analysis of HIV-1 and HIV-2 uncoating kinetics in the presence of old world monkey TRIM5α

P2860

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P2860

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

http://www.wikidata.org/entity/Q24547409

description

2006 nî lūn-bûn

@nan

2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2006年の論文

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2006年論文

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2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Specific recognition and accel ...... TRIM5alpha restriction factor

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Specific recognition and accel ...... TRIM5alpha restriction factor

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Specific recognition and accel ...... TRIM5alpha restriction factor

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type

label

Specific recognition and accel ...... TRIM5alpha restriction factor

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Specific recognition and accel ...... TRIM5alpha restriction factor

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Specific recognition and accel ...... TRIM5alpha restriction factor

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prefLabel

Specific recognition and accel ...... TRIM5alpha restriction factor

@ast

Specific recognition and accel ...... TRIM5alpha restriction factor

@en

Specific recognition and accel ...... TRIM5alpha restriction factor

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PNAS.0509996103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Specific recognition and accel ...... TRIM5alpha restriction factor

@en

P2093

Byeongwoon Song

http://www.w3.org/2001/XMLSchema#string

Donovan J Anderson

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Felipe Diaz-Griffero

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Hassan Javanbakht

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Mark Lee

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Matthew Stremlau

http://www.w3.org/2001/XMLSchema#string

Michel Perron

http://www.w3.org/2001/XMLSchema#string

Wesley I Sundquist

http://www.w3.org/2001/XMLSchema#string

Yuan Li

http://www.w3.org/2001/XMLSchema#string

P2860

TRIM5alpha selectively binds a restriction-sensitive retroviral capsid

The tripartite motif family identifies cell compartments.

TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase

BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta

Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells

Trim5alpha protein restricts both HIV-1 and murine leukemia virus

The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities

Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha

Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

Trim32 is a ubiquitin ligase mutated in limb girdle muscular dystrophy type 2H that binds to skeletal muscle myosin and ubiquitinates actin

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5514-9

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204690

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10.1073/PNAS.0509996103

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14

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103

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Joseph Sodroski

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2006-04-04T00:00:00Z

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235608224

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16540544

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1459386

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