Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway - Test2 - elhamkhani - TriplyDB

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

http://www.wikidata.org/entity/Q24550898

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Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling Smad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytes Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.Prognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancer TGF-β control of stem cell differentiation genes The links between axin and carcinogenesis Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling Enhanced Dupuytren's disease fibroblast populated collagen lattice contraction is independent of endogenous active TGF-beta2 Wnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritis Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge Normal morphogenesis of epithelial tissues and progression of epithelial tumors.Emerging roles of Axin in cerebral cortical development Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2 Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling The role of Axin2 in calvarial morphogenesis and craniosynostosis Axin2 regulates chondrocyte maturation and axial skeletal development Protein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)Endogenous transforming growth factor-beta receptor-mediated Smad signaling complexes analyzed by mass spectrometry.Xenopus Dab2 is required for embryonic angiogenesis The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin.Smad signaling in skeletal development and regeneration.Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression Wnt signalling pathway parameters for mammalian cells Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells.Intrinsic disorder in scaffold proteins: getting more from less Smad signalling in the ovary Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.TGF-β regulates β-catenin signaling and osteoblast differentiation in human mesenchymal stem cells.Two major Smad pathways in TGF-beta superfamily signalling.Role of tissue stroma in cancer cell invasion.AXIN2 rs2240308 polymorphism contributes to increased cancer risk: evidence based on a meta-analysis.Impaired neural development caused by inducible expression of Axin in transgenic mice.Hyperoxia-induced neonatal rat lung injury involves activation of TGF-{beta} and Wnt signaling and is protected by rosiglitazone -148 C/T polymorphism of Axin2 contributes to a decreased risk of cancer: evidence from a meta-analysis.TGF-beta signaling in chondrocytes.Reprogramming during epithelial to mesenchymal transition under the control of TGFβ Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering

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P2860

Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway

http://www.wikidata.org/entity/Q24550898

description

2001 nî lūn-bûn

@nan

2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Axin facilitates Smad3 activat ...... factor beta signaling pathway

@ast

Axin facilitates Smad3 activat ...... factor beta signaling pathway

@en

Axin facilitates Smad3 activat ...... factor beta signaling pathway

@nl

type

label

Axin facilitates Smad3 activat ...... factor beta signaling pathway

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Axin facilitates Smad3 activat ...... factor beta signaling pathway

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Axin facilitates Smad3 activat ...... factor beta signaling pathway

@nl

prefLabel

Axin facilitates Smad3 activat ...... factor beta signaling pathway

@ast

Axin facilitates Smad3 activat ...... factor beta signaling pathway

@en

Axin facilitates Smad3 activat ...... factor beta signaling pathway

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MCB.21.15.5132-5141.2001

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Molecular and Cellular Biology

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Axin facilitates Smad3 activat ...... factor beta signaling pathway

@en

P2093

A Kikuchi

http://www.w3.org/2001/XMLSchema#string

H Yamamoto

http://www.w3.org/2001/XMLSchema#string

K Miyazono

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K Yagi

http://www.w3.org/2001/XMLSchema#string

M Furuhashi

http://www.w3.org/2001/XMLSchema#string

M Kato

http://www.w3.org/2001/XMLSchema#string

S Shimada

http://www.w3.org/2001/XMLSchema#string

Y Furukawa

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Y Nakamura

http://www.w3.org/2001/XMLSchema#string

P2860

TGF-beta signal transduction

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

Structural basis of Smad2 recognition by the Smad anchor for receptor activation

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

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5132-41

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scholarly article

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4349056

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10.1128/MCB.21.15.5132-5141.2001

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15

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21

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2001-08-01T00:00:00Z

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11438668

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87238

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