Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
about
Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein exportNucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basketDirect interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complexAn allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell divisionCRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisNup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexesCharacterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complexCofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerComplex Commingling: Nucleoporins and the Spindle Assembly CheckpointPosttranslational marks control architectural and functional plasticity of the nuclear pore complex basketNucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin 5Nup2p dynamically associates with the distal regions of the yeast nuclear pore complex.In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of TapNuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryoTransport into and out of the nucleus.Nup50/Npap60 function in nuclear protein import complex disassembly and importin recyclingNup98 is a mobile nucleoporin with transcription-dependent dynamics.Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex.Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivoCharacterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombeThe importin β binding domain as a master regulator of nucleocytoplasmic transportNup50 is required for cell differentiation and exhibits transcription-dependent dynamics.RNA association defines a functionally conserved domain in the nuclear pore protein Nup153.A change in nuclear pore complex composition regulates cell differentiationA promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.Defects in nuclear pore assembly lead to activation of an Aurora B-mediated abscission checkpointProtein export from the nucleus.Nup2 requires a highly divergent partner, NupA, to fulfill functions at nuclear pore complexes and the mitotic chromatin region.Caspases target only two architectural components within the core structure of the nuclear pore complex.The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex.Nuclear membrane diversity: underlying tissue-specific pathologies in disease?The Nup153-Nup50 protein interface and its role in nuclear import.Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass SpectrometryRegulation of nuclear import and export of negative cofactor 2Nup214 is required for CRM1-dependent nuclear protein export in vivo.The roles of the nuclear pore complex in cellular dysfunction, aging and disease.Nuclear pore complex assembly and maintenance in POM121- and gp210-deficient cells
P2860
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P2860
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@ast
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@en
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@nl
type
label
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@ast
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@en
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@nl
prefLabel
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@ast
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@en
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@nl
P2093
P2860
P1476
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export
@en
P2093
A Kehlenbach
B E Clurman
E C Schirmer
R H Kehlenbach
P2860
P304
P356
10.1128/MCB.20.15.5619-5630.2000
P407
P577
2000-08-01T00:00:00Z