Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer - Test2 - elhamkhani - TriplyDB

Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer

Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer

http://www.wikidata.org/entity/Q24803723

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Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor Differential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesis Essential function for ErbB3 in breast cancer proliferation Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis.Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis.Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids.The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.miR-221/222 compensates for Skp2-mediated p27 degradation and is a primary target of cell cycle regulation by prostacyclin and cAMP Binding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms.Histological and immunohistochemical markers for progression prediction in transurethrally resected high-grade non-muscle invasive bladder cancer.Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27 Regulation of hematopoietic stem cell growth.Semi-quantitative scoring of potentially predictive markers for endocrine treatment of breast cancer: a comparison between whole sections and tissue microarrays.A crosstalk imbalance between p27(Kip1) and its interacting molecules enhances breast carcinogenesis Genetic Association Between CDKN1B rs2066827 Polymorphism and Susceptibility to Cancer.An essential role of p27 downregulation in fenvalerate-induced cell growth in human uterine leiomyoma and smooth muscle cells.Targeting the ubiquitin-proteasome pathway in breast cancer therapy.Endothelin-1 couples betaPix to p66Shc: role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of Akt Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27 Presence of HER4 associates with increased sensitivity to Herceptin in patients with metastatic breast cancer.Expression of p27Kip1, a cell cycle repressor protein, is inversely associated with potential carcinogenic risk in the genetic rodent models of obesity and long-lived Ames dwarf mice.Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer β1-integrin controls cell fate specification in early lens development.Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context.Mechanism of the anti-cancer activity of Zizyphus jujuba in HepG2 cells.Effect of p27(KIP1) on cell cycle and apoptosis in gastric cancer cells.Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal hydrolase 1 (UCHL-1) in human myeloma cells.Regulation of p27Kip1 phosphorylation and G1 cell cycle progression by protein phosphatase PPM1G.p27KIP1 expression in gastric cancer: differential pathways in the histological subtypes associated with Helicobacter pylori infection.Association of CDKN1B gene polymorphisms with susceptibility to breast cancer: a meta-analysis.PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells.Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells.Overexpression of phosphorylated p27 Kip1 at threonine 187 may predict outcome in aggressive B-cell lymphomas.PTEN/Akt-p27(kip1) Signaling Promote the BM-MSCs Senescence and Apoptosis in SLE Patients.Expression of p27 and c-Myc by immunohistochemistry in breast ductal cancers in African American women.Biofunctional characteristics of in situ and invasive breast carcinoma.The V109G polymorphism of the p27 gene CDKN1B indicates a worse outcome in node-negative breast cancer patients.

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P2860

Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer

http://www.wikidata.org/entity/Q24803723

description

2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Breast Cancer Research

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Deregulation of p27 by oncogen ...... significance in breast cancer

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Angel Alkarain

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Joyce Slingerland

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P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

New functional activities for the p21 family of CDK inhibitors

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export

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10.1186/BCR722

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1

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1041269220

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breast neoplasm

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314445

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