Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division
about
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separaseA human protein related to yeast Cdc6pChromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosisThe Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeastCdc6 protein causes premature entry into S phase in a mammalian cell-free system.Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpointHuman Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosisIdentification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phaseRegulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strainsSPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.Reverse genetic analysis of the yeast RSC chromatin remodeler reveals a role for RSC3 and SNF5 homolog 1 in ploidy maintenanceThe B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutantsCdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint.The REC1 gene of Ustilago maydis, which encodes a 3'-->5' exonuclease, couples DNA repair and completion of DNA synthesis to a mitotic checkpoint.Establishing genetic interactions by a synthetic dosage lethality phenotype.Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitroThe Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin.Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exitUnphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycleRoles of the CDK phosphorylation sites of yeast Cdc6 in chromatin binding and rereplication.A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle.CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication.Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiaeXenopus Cdc6 confers sperm binding competence to oocytes without inducing their maturation.De novo synthesis of budding yeast DNA polymerase alpha and POL1 transcription at the G1/S boundary are not required for entrance into S phaseTwo fission yeast B-type cyclins, cig2 and Cdc13, have different functions in mitosis.Characterization of a novel CDC gene (ORC1) partly homologous to CDC6 of Saccharomyces cerevisiae.Negative regulation of Cdc18 DNA replication protein by Cdc2.Cell cycle regulation of DNA replication.Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.Centromere replication timing determines different forms of genomic instability in Saccharomyces cerevisiae checkpoint mutants during replication stress.Phosphorylation controls timing of Cdc6p destruction: A biochemical analysisHuman replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1.
P2860
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P2860
Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@ast
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@en
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@nl
type
label
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@ast
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@en
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@nl
prefLabel
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@ast
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@en
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@nl
P2860
P1433
P1476
Dual functions of CDC6: a yeas ...... also inhibits nuclear division
@en
P2093
P2860
P304
P407
P577
1992-06-01T00:00:00Z