PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73 - Test2 - elhamkhani - TriplyDB

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

http://www.wikidata.org/entity/Q24559766

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PIAS1 interacts with FLASH and enhances its co-activation of c-Myb Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins FLASH is essential during early embryogenesis and cooperates with p73 to regulate histone gene transcription Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP FLASH is required for histone transcription and S-phase progression FLASH is an essential component of Cajal bodies Regulation of gene-activation pathways by PIAS proteins in the immune system Phosphorylation of Ubc9 by Cdk1 enhances SUMOylation activity Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone.Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5.Alteration of nuclear matrix-intermediate filament system and differential expression of nuclear matrix proteins during human hepatocarcinoma cell differentiation.Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors Cytokine-induced tumor suppressors: a GRIM story p53 Family and Cellular Stress Responses in Cancer.PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells Ubiquitin and ubiquitin-like modifications of the p53 family.Regulation of p73 activity by post-translational modifications.Opposing actions of STAT-1 and STAT-3.Cataloging and organizing p73 interactions in cell cycle arrest and apoptosis PIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer.A gene signature-based approach identifies mTOR as a regulator of p73.TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene.An overview of stress response and hypometabolic strategies in Caenorhabditis elegans: conserved and contrasting signals with the mammalian system.p53-family proteins and their regulators: hubs and spokes in tumor suppression.Functions, divergence and clinical value of TAp73 isoforms in cancer.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.p73 expression is regulated by ribosomal protein RPL26 through mRNA translation and protein stability.FLASH degradation in response to UV-C results in histone locus bodies disruption and cell-cycle arrest.Protein kinase C-dependent phosphorylation regulates the cell cycle-inhibitory function of the p73 carboxy terminus transactivation domain.Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.TIP60 represses transcriptional activity of p73beta via an MDM2-bridged ternary complex.PIASy controls ubiquitination-dependent proteasomal degradation of Ets-1.Generation of DeltaTAp73 proteins by translation from a putative internal ribosome entry site.S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulation Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function.

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PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

http://www.wikidata.org/entity/Q24559766

description

2004 nî lūn-bûn

@nan

2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

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2004年論文

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2004年論文

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2004年論文

@zh-hk

2004年論文

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2004年論文

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2004年论文

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name

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

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PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

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PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

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type

label

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

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PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

@en

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

@nl

prefLabel

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

@ast

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

@en

PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

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MCB.24.24.10593-10610.2004

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Molecular and Cellular Biology

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PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73

@en

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Anastasis Stephanou

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Carine Maisse

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Daniela Barcaroli

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David S Latchman

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Eliana Munarriz

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Gerry Melino

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Michael H Neale

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Paul A Townsend

http://www.w3.org/2001/XMLSchema#string

Richard A Knight

http://www.w3.org/2001/XMLSchema#string

P2860

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction

NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers

Inhibition of Stat1-mediated gene activation by PIAS1

SUMO-1 modification activates the transcriptional response of p53

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

Improved method for high efficiency transformation of intact yeast cells

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

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10593-610

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scholarly article

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10.1128/MCB.24.24.10593-10610.2004

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24

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24

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Alessandro Terrinoni

Seamus J. Martin

Vincenzo De Laurenzi

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2004-12-01T00:00:00Z

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15572666

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533962

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