PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
about
NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomersPIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunitPIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxiaPIAS1 interacts with FLASH and enhances its co-activation of c-MybTopors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motifRegulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteinsSUMOylation enhances DNA methyltransferase 1 activityPotentiation of serum response factor activity by a family of myocardin-related transcription factors.SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cyclePARP-1 transcriptional activity is regulated by sumoylation upon heat shockRegulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications.Sumoylation of the zinc finger protein ZXDC enhances the function of its transcriptional activation domainNARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.SUMO represses transcriptional activity of the Drosophila SoxNeuro and human Sox3 central nervous system-specific transcription factors.Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation.Principles of interleukin (IL)-6-type cytokine signalling and its regulationModification with SUMO. A role in transcriptional regulationTranscription factor Sp3 is silenced through SUMO modification by PIAS1The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylaseDesumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin.Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxbeta.Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signalingRole for SUMO modification in facilitating transcriptional repression by BKLF.PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult lifeInteraction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBPWnt/beta-catenin signaling and small molecule inhibitorsSUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expressionActivation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNAHistone sumoylation is associated with transcriptional repressionDazap2 modulates transcription driven by the Wnt effector TCF-4A functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathwaySumoylation is involved in beta-catenin-dependent activation of Tcf-4Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells
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P2860
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@ast
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@en
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@nl
type
label
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@ast
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@en
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@nl
prefLabel
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@ast
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@en
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@nl
P2093
P2860
P921
P356
P1433
P1476
PIASy, a nuclear matrix-associ ...... uestration into nuclear bodies
@en
P2093
P2860
P304
P356
10.1101/GAD.944801
P407
P577
2001-12-01T00:00:00Z