Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas
about
Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gammaA novel regulatory mechanism links PLCγ1 to PDK1The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-KitPhospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase CTyrosine kinase signalling in breast cancer: modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediates.Phosphoinositides: tiny lipids with giant impact on cell regulationThe phospholipase C isozymes and their regulationDemonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptorsThe protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesionComputational Identification of Novel Stage-Specific Biomarkers in Colorectal Cancer ProgressionAbsence of erythrogenesis and vasculogenesis in Plcg1-deficient miceThe role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptorsrc-homology 2 (SH2) domain ligation as an allosteric regulator: modulation of phosphoinositide-specific phospholipase C gamma 1 structure and activity.A thirteen-gene expression signature predicts survival of patients with pancreatic cancer and identifies new genes of interest.Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptorsPhospholipase C-gamma1 is required for the epidermal growth factor receptor-induced squamous cell carcinoma cell mitogenesis.In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.Critical role for the catalytic activity of phospholipase C-gamma1 in epidermal growth factor-induced cell migration.FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.Chronic pancreatitis is associated with increased concentrations of epidermal growth factor receptor, transforming growth factor alpha, and phospholipase C gamma.Genetic mapping of the human and mouse phospholipase C genes.Recursive SVM biomarker selection for early detection of breast cancer in peripheral bloodThe inhibition of the estrogenic effects of pesticides and environmental chemicals by curcumin and isoflavonoids.Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptorsOverexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alphaAngiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and developmentConstitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.Epidermal growth factor stimulates substrate-selective protein-tyrosine-phosphatase activitySynergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice.Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity.Cloning of the human phospholipase C-gamma1 promoter and identification of a DR6-type vitamin D-responsive element.Hyperexpression of mitogen-activated protein kinase in human breast cancer.Characterization of phospholipase C gamma enzymes with gain-of-function mutations.In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasivenessEnhanced phospholipase C-gamma1 activity produced by association of independently expressed X and Y domain polypeptides.Investigational platelet-derived growth factor receptor kinase inhibitors in breast cancer therapy.Integrative analysis of a cancer somatic mutome.U-73122 reduces the cell growth in cultured MG-63 ostesarcoma cell line involving Phosphoinositide-specific Phospholipases C.
P2860
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P2860
Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas
description
1991 nî lūn-bûn
@nan
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Elevated content of the tyrosi ...... rimary human breast carcinomas
@ast
Elevated content of the tyrosi ...... rimary human breast carcinomas
@en
Elevated content of the tyrosi ...... rimary human breast carcinomas
@nl
type
label
Elevated content of the tyrosi ...... rimary human breast carcinomas
@ast
Elevated content of the tyrosi ...... rimary human breast carcinomas
@en
Elevated content of the tyrosi ...... rimary human breast carcinomas
@nl
prefLabel
Elevated content of the tyrosi ...... rimary human breast carcinomas
@ast
Elevated content of the tyrosi ...... rimary human breast carcinomas
@en
Elevated content of the tyrosi ...... rimary human breast carcinomas
@nl
P2093
P2860
P3181
P356
P1476
Elevated content of the tyrosi ...... rimary human breast carcinomas
@en
P2093
C L Arteaga
G Carpenter
G Todderud
M D Johnson
R J Coffey
P2860
P304
P3181
P356
10.1073/PNAS.88.23.10435
P407
P577
1991-12-01T00:00:00Z