Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas - Test2 - elhamkhani - TriplyDB

Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas

Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas

http://www.wikidata.org/entity/Q24559979

about

Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma A novel regulatory mechanism links PLCγ1 to PDK1 The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C Tyrosine kinase signalling in breast cancer: modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediates.Phosphoinositides: tiny lipids with giant impact on cell regulation The phospholipase C isozymes and their regulation Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors The protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesion Computational Identification of Novel Stage-Specific Biomarkers in Colorectal Cancer Progression Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor src-homology 2 (SH2) domain ligation as an allosteric regulator: modulation of phosphoinositide-specific phospholipase C gamma 1 structure and activity.A thirteen-gene expression signature predicts survival of patients with pancreatic cancer and identifies new genes of interest.Physiological requirement for both SH2 domains for phospholipase C-gamma1 function and interaction with platelet-derived growth factor receptors Phospholipase C-gamma1 is required for the epidermal growth factor receptor-induced squamous cell carcinoma cell mitogenesis.In vitro and in vivo effects of suppressor of cytokine signalling 7 knockdown in breast cancer: the influence on cellular response to hepatocyte growth factor.Critical role for the catalytic activity of phospholipase C-gamma1 in epidermal growth factor-induced cell migration.FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms.Chronic pancreatitis is associated with increased concentrations of epidermal growth factor receptor, transforming growth factor alpha, and phospholipase C gamma.Genetic mapping of the human and mouse phospholipase C genes.Recursive SVM biomarker selection for early detection of breast cancer in peripheral blood The inhibition of the estrogenic effects of pesticides and environmental chemicals by curcumin and isoflavonoids.Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.Epidermal growth factor stimulates substrate-selective protein-tyrosine-phosphatase activity Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice.Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity.Cloning of the human phospholipase C-gamma1 promoter and identification of a DR6-type vitamin D-responsive element.Hyperexpression of mitogen-activated protein kinase in human breast cancer.Characterization of phospholipase C gamma enzymes with gain-of-function mutations.In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasiveness Enhanced phospholipase C-gamma1 activity produced by association of independently expressed X and Y domain polypeptides.Investigational platelet-derived growth factor receptor kinase inhibitors in breast cancer therapy.Integrative analysis of a cancer somatic mutome.U-73122 reduces the cell growth in cultured MG-63 ostesarcoma cell line involving Phosphoinositide-specific Phospholipases C.

P2860

Q24293518-C115F258-52E8-4D79-A804-790A69CD7436 Q24310088-68D8DCAA-BF27-4ACC-A489-775E8E6B2C9C Q24535600-FDAB08DB-B97B-4169-AB25-BDB015729E16 Q24561989-2A111C5B-7A8F-4FC7-9E66-8498A45B2345 Q24803027-E577C623-BC11-4CE2-958E-37325C4C4D0F Q27012953-7D481C25-86D4-4921-9DFB-FA32E11F01CE Q28261474-4AF9DDA0-17D1-4E22-9EF5-B43BFF610DAD Q28287661-DF317A34-6203-413C-A4F9-0815F68334B4 Q28512484-47B23E85-F493-4871-B0A9-53F2BBA3709F Q28552533-69259BE4-62A1-41A8-8F24-4E28E0528060 Q28591776-F645C4D8-C1DB-49E9-83C4-516B27181B95 Q28678514-539611AF-E854-4676-A63F-569B9CE7C2DA Q30193694-4527B108-3151-48F6-BB59-5A6B255D93E9 Q30410836-8979F18C-D678-43FA-B957-139D0D3E8152 Q33958685-13D081AB-BCFB-4837-842F-03EAE93C0FA9 Q33982851-9E4E127F-08C9-48CF-B27F-8986505E7641 Q34064613-BC438A56-28B5-4BB9-A9E1-78784577A7DD Q34104448-527DFB30-8666-4A26-80F2-9DC69E1D67A4 Q34305855-95581C38-FFE6-40F3-BE76-D946D4AE9D34 Q34379846-96C738B8-77B1-47BF-B0AA-A68BCE200B6F Q34385771-3E5F7B99-C4BF-4B39-9DD7-E361A3FC1F51 Q34570165-7D8BE59A-5098-47C2-AC18-E38662CDB810 Q34939904-A8BC56C4-FDA8-4503-9DC6-A49D9D18860B Q35236031-35F814D3-342C-4581-B079-D7206066BDEE Q35606708-92EF479B-0D72-4629-941A-9AAB7279A0E3 Q36014526-EEA2AE57-4FEE-4172-9262-CF31DFE79695 Q36066649-9861DD75-DF0F-48D4-88B6-BA281F62D7B4 Q36074211-9A0B622F-05A7-4D71-8AA3-717F7DFC0E29 Q36274343-3D442616-9020-4A75-9ED8-A19F3B46EF37 Q36484874-AA84A465-F70D-4D34-8439-729FF2EB15B0 Q36563002-4FA123E5-E98A-4ADB-B310-F9B83B70793F Q36644521-1F054709-92D1-427B-999B-8FDE8FBFB210 Q36847893-44C8D4B1-67F1-44B0-A55E-9A92F5C238D1 Q37365431-E973E1ED-4A16-4E98-A7EC-8896AED404E5 Q37371736-1175DFEF-6C6F-4910-9434-380051171798 Q37399964-3F7E6A90-394D-4282-86F9-997E59E600E3 Q37424515-232634D6-8596-4533-B01E-148C91F3E252 Q38193533-4ACE9999-12E1-4BB6-9401-4D539FE640CF Q38516793-8015020C-FC65-4AC3-9354-0F61C3E269D2 Q38619801-6A36DDDA-72E8-48CA-8A01-8BFEC031AB34

P2860

Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas

http://www.wikidata.org/entity/Q24559979

description

1991 nî lūn-bûn

@nan

1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1991年の論文

@ja

1991年論文

@yue

1991年論文

@zh-hant

1991年論文

@zh-hk

1991年論文

@zh-mo

1991年論文

@zh-tw

1991年论文

@wuu

name

Elevated content of the tyrosi ...... rimary human breast carcinomas

@ast

Elevated content of the tyrosi ...... rimary human breast carcinomas

@en

Elevated content of the tyrosi ...... rimary human breast carcinomas

@nl

type

label

Elevated content of the tyrosi ...... rimary human breast carcinomas

@ast

Elevated content of the tyrosi ...... rimary human breast carcinomas

@en

Elevated content of the tyrosi ...... rimary human breast carcinomas

@nl

prefLabel

Elevated content of the tyrosi ...... rimary human breast carcinomas

@ast

Elevated content of the tyrosi ...... rimary human breast carcinomas

@en

Elevated content of the tyrosi ...... rimary human breast carcinomas

@nl

P1433

Q24559979-0751430B-569C-4E64-96DF-6F73109C4D59

P1476

Q24559979-7D6DFD5E-B017-4685-823D-D4D7017E0CE2

P2093

Q24559979-5395DE8E-919E-497D-AA89-5F232EFFF507

Q24559979-754A039A-EAE7-47AD-813A-729C31DA5C3F

Q24559979-779086B8-35C5-4B02-99D7-F6F6F441A48F

Q24559979-7E5597CC-35F3-4BD4-B5A7-81DD25DEBD16

Q24559979-9DD22BC5-CF32-4C6E-A034-09D54719CEA3

Q24559979-ACCCDF1C-283B-4D02-8AB0-23898A97D746

P2860

Q24559979-0AF87746-DF19-4CC2-8A00-AC901DE725D0

Q24559979-0E96C8F8-EE2E-4203-8831-8A2F5ED675AA

Q24559979-1A98AAED-F554-4F30-8A0C-9E66799A4563

Q24559979-1E052E1E-A11E-4398-8345-E2A954EF1BA7

Q24559979-20E5A762-9D70-4F67-A459-841ED9B3279A

Q24559979-23F36A87-DD8B-486A-A249-38106AC374E3

Q24559979-2F0F3F55-FC2D-40A2-A3E4-4FA41DD97085

Q24559979-351D9366-6D23-4A39-A472-54D125C3117F

Q24559979-376AA156-2B20-4A03-881B-A78F4AAE3BA0

Q24559979-37C01F76-5321-4B78-B316-D98B3E33DAF3

P304

Q24559979-B5073974-62DE-4ABB-B106-961FC7595115

P31

Q24559979-8CFC14ED-4111-4CCB-B104-BCACDCC4ECCC

P3181

Q24559979-A4C4C615-AE13-412D-9102-EB584C3C8348

P356

Q24559979-9312F2CE-5F30-4146-8A3E-F849581C5693

P407

Q24559979-40113C0B-15C2-4C85-A17D-B8CA48BF791B

P433

Q24559979-1D9C09A8-7B4A-4719-B8F2-DF41DE48DACA

P478

Q24559979-79E661F2-235C-498D-8739-8C6795DEFB2D

P577

Q24559979-BC44BC08-A45D-47D7-A239-BAD6047AF192

P5875

Q24559979-86D4E102-0876-4FF2-99A3-C72FB17E0342

P698

Q24559979-47653757-04A5-401C-A5A4-230097B30819

P932

Q24559979-A089507C-AFC0-4FB3-BC70-7DC5343885E3

P3181

P356

PNAS.88.23.10435

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Elevated content of the tyrosi ...... rimary human breast carcinomas

@en

P2093

C L Arteaga

http://www.w3.org/2001/XMLSchema#string

D L Page

http://www.w3.org/2001/XMLSchema#string

G Carpenter

http://www.w3.org/2001/XMLSchema#string

G Todderud

http://www.w3.org/2001/XMLSchema#string

M D Johnson

http://www.w3.org/2001/XMLSchema#string

R J Coffey

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

A second type of rat phosphoinositide-specific phospholipase C containing a src-related sequence not essential for phosphoinositide-hydrolyzing activity

Identification of two epidermal growth factor-sensitive tyrosine phosphorylation sites of phospholipase C-gamma in intact HSC-1 cells

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency

Phospholipase C gamma complexes with ligand-activated platelet-derived growth factor receptors. An intermediate implicated in phospholipase activation.

Antibody to phosphatidylinositol 4,5-bisphosphate inhibits oncogene-induced mitogenesis.

Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.

Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines

P304

10435-9

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1162658

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.88.23.10435

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

88

http://www.w3.org/2001/XMLSchema#string

P577

1991-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

253831805

http://www.w3.org/2001/XMLSchema#string

P698

1683701

http://www.w3.org/2001/XMLSchema#string

P932

52943

http://www.w3.org/2001/XMLSchema#string