The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction
about
Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductaseOxidative-stress resistance mutants of Helicobacter pylori.Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and releaseImplications of NQO1 in cancer therapyThe flavoproteome of the yeast Saccharomyces cerevisiaeUpdate of the NAD(P)H:quinone oxidoreductase (NQO) gene familyNADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transferStructures of nitroreductase in three states: effects of inhibitor binding and reductionCrystal Structures of the Quinone Oxidoreductase from Thermus thermophilus HB8 and Its Complex with NADPH: Implication for NADPH and Substrate RecognitionExpansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesisKTN (RCK) Domains Regulate K+ Channels and Transporters by Controlling the Dimer-Hinge ConformationA single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductaseRole of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazideThe structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substratesMechanistic and structural basis for inhibition of thymidylate synthase ThyXMolecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrRActivation of nitrofurazone by azoreductases: multiple activities in one enzymeThe Structural and Functional Basis of Catalysis Mediated by NAD(P)H:acceptor Oxidoreductase (FerB) of Paracoccus denitrificans1.2 Å resolution crystal structure of Escherichia coli WrbA holoproteinThe crystal structure of Pseudomonas putida azoreductase - the active site revisitedStructural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductaseStructural views of quinone oxidoreductase from Mycobacterium tuberculosis reveal large conformational changes induced by the co-factorLot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification.Crystal structure of quinone reductase 2 in complex with resveratrolFunctional Annotation of a Presumed Nitronate Monoxygenase Reveals a New Class of NADH:Quinone ReductasesStructure determination of an FMN reductase from Pseudomonas aeruginosa PA01 using sulfur anomalous signalNovel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosisFlavin fluorescence dynamics and photoinduced electron transfer in Escherichia coli glutathione reductaseGenomic exploration of the hemiascomycetous yeasts: 6. Saccharomyces exiguus.Mutation of cytotoxin-associated gene A affects expressions of antioxidant proteins of Helicobacter pyloriBiphasic kinetic behavior of E. coli WrbA, an FMN-dependent NAD(P)H:quinone oxidoreductaseThe diverse antioxidant systems of Helicobacter pylori.Reaction mechanism of single subunit NADH-ubiquinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae: evidence for a ternary complex mechanism.A mechanistic and structural analysis of the inhibition of the 90-kDa heat shock protein by the benzoquinone and hydroquinone ansamycins.NAD(P)H:quinone oxidoreductase 1 Arg139Trp and Pro187Ser polymorphisms imbalance estrogen metabolism towards DNA adduct formation in human mammary epithelial cells.Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence.A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.Quinone reductases multitasking in the metabolic world.Evidence from ESI-MS for NQO1-catalyzed reduction of estrogen ortho-quinones
P2860
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P2860
The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
The three-dimensional structur ...... of the two-electron reduction
@ast
The three-dimensional structur ...... of the two-electron reduction
@en
The three-dimensional structur ...... of the two-electron reduction
@nl
type
label
The three-dimensional structur ...... of the two-electron reduction
@ast
The three-dimensional structur ...... of the two-electron reduction
@en
The three-dimensional structur ...... of the two-electron reduction
@nl
prefLabel
The three-dimensional structur ...... of the two-electron reduction
@ast
The three-dimensional structur ...... of the two-electron reduction
@en
The three-dimensional structur ...... of the two-electron reduction
@nl
P2093
P2860
P3181
P356
P1476
The three-dimensional structur ...... of the two-electron reduction
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.92.19.8846
P407
P577
1995-09-12T00:00:00Z