Structures of nitroreductase in three states: effects of inhibitor binding and reduction
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Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glandsStructure and Function of CinD (YtjD) of Lactococcus lactis, a Copper-Induced Nitroreductase Involved in Defense against Oxidative StressStructure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pyloriCrystal Structure of Reduced MsAcg, a Putative Nitroreductase from Mycobacterium smegmatis and a Close Homologue of Mycobacterium tuberculosis AcgActivation of nitrofurazone by azoreductases: multiple activities in one enzymeCrystallization and preliminary analysis of active nitroalkane oxidase in three crystal formsCharacterization of a pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2-nitrobenzoate chemotaxis.A temperature-dependent conformational change of NADH oxidase from Thermus thermophilus HB8.Structural and Mechanistic Insights into the Pseudomonas fluorescens 2-Nitrobenzoate 2-Nitroreductase NbaASingle Amino Acid Switch between a Flavin-Dependent Dehalogenase and Nitroreductase.Crystallization and preliminary X-ray diffraction analysis of ydjA, a minimal nitroreductase from Escherichia coli K12.Reduction of polynitroaromatic compounds: the bacterial nitroreductases.Functional characterization of the re-face loop spanning residues 536-541 and its interactions with the cofactor in the flavin mononucleotide-binding domain of flavocytochrome P450 from Bacillus megaterium.The distribution and mechanism of iodotyrosine deiodinase defied expectations.Crystal structures of two nitroreductases from hypervirulent Clostridium difficile and functionally related interactions with the antibiotic metronidazole.Engineering towards nitroreductase functionality in ene-reductase scaffolds.Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state.Understanding the broad substrate repertoire of nitroreductase based on its kinetic mechanism.Microbial responses to xenobiotic compounds. Identification of genes that allow Pseudomonas putida KT2440 to cope with 2,4,6-trinitrotolueneLigand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding.Role of conformational flexibility for enzymatic activity in NADH oxidase from Thermus thermophilus.Residue Phe42 is critical for the catalytic activity of Escherichia coli major nitroreductase NfsA.Modulation of activity of NADH oxidase from Thermus thermophilus through change in flexibility in the enzyme active site induced by Hofmeister series anions.Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.Equilibrium and ultrafast kinetic studies manipulating electron transfer: A short-lived flavin semiquinone is not sufficient for electron bifurcation.PnrA, a new nitroreductase-family enzyme in the TNT-degrading strain Pseudomonas putida JLR11.In silico structure-function analysis of E. cloacae nitroreductase.Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase.Conversion of a Dehalogenase into a Nitroreductase by Swapping its Flavin Cofactor with a 5-Deazaflavin Analogue.Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase.Three-dimensional structure of AzoR from Escherichia coli. An oxidereductase conserved in microorganisms.Drug design based on pentaerythritol tetranitrate reductase: synthesis and antibacterial activity of Pogostone derivatives.Использование интеллектуальной ДСМ-системы для анализа связи структуры нитрозамещенных бензолов с их мутагенной активностью в тесте Эймса
P2860
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P2860
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@ast
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@en
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@nl
type
label
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@ast
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@en
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@nl
prefLabel
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@ast
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@en
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@nl
P2093
P2860
P356
P1476
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
@en
P2093
Anne-Frances Miller
Chad A Haynes
David W Rodgers
Ronald L Koder
P2860
P304
P356
10.1074/JBC.M111334200
P407
P577
2002-03-29T00:00:00Z