Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases
about
Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesisProfiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CMLInterleukin-6, CD45 and the src-kinases in myeloma cell proliferationHS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cellsNeutrophil cell surface receptors and their intracellular signal transduction pathways.Suppression of apoptosis induced by growth factor withdrawal by an oncogenic form of c-Cbl.Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis.Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemiaThe tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distancesHematopoietic colony-stimulating factors: new players in tumor-nerve interactions.Highly metastatic 13762NF rat mammary adenocarcinoma cell clones stimulate bone marrow by secretion of granulocyte-macrophage colony-stimulating factor/interleukin-3 activitySrc family kinases are important negative regulators of G-CSF-dependent granulopoiesisSpleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis.The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathwaySustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene.Agents under investigation for the treatment and prevention of neutropenia.Src family kinases and the MEK/ERK pathway in the regulation of myeloid differentiation and myeloid leukemogenesisThe new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatmentNeutropenia with impaired host defense against microbial infection in mice lacking androgen receptor.Multiple roles of Lyn kinase in myeloid cell signaling and function.G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation.Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells.Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy.Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.Systems approach to phagocyte production and activation: neutrophils and monocytes.Kinase activation of the non-receptor tyrosine kinase Etk/BMX alone is sufficient to transactivate STAT-mediated gene expression in salivary and lung epithelial cells.Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation.Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies.Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathwayG-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth.Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase.Distinct signal transduction through the tyrosine-containing domains of the granulocyte colony-stimulating factor receptor.Ras and signal transducer and activator of transcription (STAT) are essential and sufficient downstream components of Janus kinases in cell proliferation.Physical and functional interaction between p72(syk) and erythropoietin receptor.Conditional activation of Janus kinase (JAK) confers factor independence upon interleukin-3-dependent cells. Essential role of Ras in JAK-triggered mitogenesis.Requirement of Src kinase Lyn for induction of DNA synthesis by granulocyte colony-stimulating factor.
P2860
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P2860
Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@ast
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@en
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@nl
type
label
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@ast
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@en
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@nl
prefLabel
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@ast
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@en
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@nl
P2093
P2860
P356
P1476
Granulocyte colony-stimulating ...... d Syk protein-tyrosine kinases
@en
P2093
A L Burkhardt
D J Tweardy
L S Tkatch
P2860
P304
P356
10.1073/PNAS.91.11.4683
P407
P577
1994-05-01T00:00:00Z