A family of potassium channel genes related to eag in Drosophila and mammals
about
Eag and HERG potassium channels as novel therapeutic targets in cancerNew ether-à-go-go K(+) channel family members localized in human telencephalonRescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channelsThe human delta1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expressionCloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusionInteractive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channelsA novel role for HERG K+ channels: spike-frequency adaptationBmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currentsMarine algal toxin azaspiracid is an open-state blocker of hERG potassium channelsRole of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmiasA recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channelsThe antipsychotic drug chlorpromazine inhibits HERG potassium channelshERG1 Potassium Channels: Novel Biomarkers in Human Solid CancershERG channel function: beyond long QTTranslational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspectsVoltage-gated ion channels in cancer cell proliferationNovel roles for hERG K(+) channels in cell proliferation and apoptosisMechanistic Insight into Human ether-a-go-go-related Gene (hERG) K+ Channel Deactivation Gating from the Solution Structure of the EAG DomainProtein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeationStructural properties of PAS domains from the KCNH potassium channelsStructure of the C-terminal region of an ERG channel and functional implicationsMolecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium ChannelA structural basis for drug-induced long QT syndromeInhibition of HERG1 K(+) channels by the novel second-generation antihistamine mizolastineModulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascadeCorrection of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effectsRegulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen speciesCarboxy-terminal domain mediates assembly of the voltage-gated rat ether-à-go-go potassium channelProperties of HERG channels stably expressed in HEK 293 cells studied at physiological temperatureIdentifying regulators for EAG1 channels with a novel electrophysiology and tryptophan fluorescence based screenRapid internalization of the oncogenic K+ channel K(V)10.1Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutationChanges in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channelA molecular switch driving inactivation in the cardiac K+ channel HERGAbnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1Alcohol-induced histone acetylation reveals a gene network involved in alcohol toleranceMolecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine MyocardiumSubcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heartCloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic gangliaThe subfamily-specific assembly of Eag and Erg K+ channels is determined by both the amino and the carboxyl recognition domains
P2860
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P2860
A family of potassium channel genes related to eag in Drosophila and mammals
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A family of potassium channel genes related to eag in Drosophila and mammals
@ast
A family of potassium channel genes related to eag in Drosophila and mammals
@en
A family of potassium channel genes related to eag in Drosophila and mammals
@nl
type
label
A family of potassium channel genes related to eag in Drosophila and mammals
@ast
A family of potassium channel genes related to eag in Drosophila and mammals
@en
A family of potassium channel genes related to eag in Drosophila and mammals
@nl
prefLabel
A family of potassium channel genes related to eag in Drosophila and mammals
@ast
A family of potassium channel genes related to eag in Drosophila and mammals
@en
A family of potassium channel genes related to eag in Drosophila and mammals
@nl
P2860
P3181
P356
P1476
A family of potassium channel genes related to eag in Drosophila and mammals
@en
P2093
B Ganetzky
J W Warmke
P2860
P304
P3181
P356
10.1073/PNAS.91.8.3438
P407
P577
1994-04-12T00:00:00Z