Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels
about
Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophyHypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.A mechanism for combinatorial regulation of electrical activity: Potassium channel subunits capable of functioning as Src homology 3-dependent adaptorsMolecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testisDifferent roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channelsRegulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regionsDifferential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampusProperties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotideC-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gatingLocalization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturationThe N2-Src neuronal splice variant of C-Src has altered SH3 domain ligand specificity and a higher constitutive activity than N1-Src.HCN1 channels in cerebellar Purkinje cells promote late stages of learning and constrain synaptic inhibitionSuppression of ih contributes to propofol-induced inhibition of mouse cortical pyramidal neurons.The pelvis-kidney junction contains HCN3, a hyperpolarization-activated cation channel that triggers ureter peristalsis.Regulation of the voltage-gated K+ channel KCNA10 by KCNA4B, a novel beta-subunit.Molecular characterization, functional expression, and developmental profile of an ether à-go-go K+ channel in the tobacco hornworm Manduca sexta.High I(h) channel density in the distal apical dendrite of layer V pyramidal cells increases bidirectional attenuation of EPSPs.Molecular cloning of a putative cyclic nucleotide-gated ion channel cDNA from Limulus polyphemus.Computation by oscillations: implications of experimental data for theoretical models of grid cells.Expression of key ion channels in the rat cardiac conduction system by laser capture microdissection and quantitative real-time PCR.Chronic cervical radiculopathic pain is associated with increased excitability and hyperpolarization-activated current ( Ih) in large-diameter dorsal root ganglion neuronsKCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels.Pacemaker oscillations in heart and brain: a key role for hyperpolarization-activated cation channels.Assessing the role of Ih channels in synaptic transmission and mossy fiber LTP.Rundown of the hyperpolarization-activated KAT1 channel involves slowing of the opening transitions regulated by phosphorylation.Axon physiology.Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.Combinatorial control of a neuron-specific exonTargeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Unzipping ion channels.Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.Properties of ivabradine-induced block of HCN1 and HCN4 pacemaker channels.Molecular mechanism underlying phosphatidylinositol 4,5-bisphosphate-induced inhibition of SpIH channels.Distribution and function of HCN channels in the apical dendritic tuft of neocortical pyramidal neuronsQuantitative analysis and subcellular distribution of mRNA and protein expression of the hyperpolarization-activated cyclic nucleotide-gated channels throughout development in rat hippocampus.The fast and slow ups and downs of HCN channel regulation.Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouseConstitutively active Src tyrosine kinase changes gating of HCN4 channels through direct binding to the channel proteins.The multiple personalities of h-channels
P2860
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P2860
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Interactive cloning with the S ...... clic nucleotide-gated channels
@ast
Interactive cloning with the S ...... clic nucleotide-gated channels
@en
Interactive cloning with the S ...... clic nucleotide-gated channels
@en-gb
Interactive cloning with the S ...... clic nucleotide-gated channels
@nl
type
label
Interactive cloning with the S ...... clic nucleotide-gated channels
@ast
Interactive cloning with the S ...... clic nucleotide-gated channels
@en
Interactive cloning with the S ...... clic nucleotide-gated channels
@en-gb
Interactive cloning with the S ...... clic nucleotide-gated channels
@nl
prefLabel
Interactive cloning with the S ...... clic nucleotide-gated channels
@ast
Interactive cloning with the S ...... clic nucleotide-gated channels
@en
Interactive cloning with the S ...... clic nucleotide-gated channels
@en-gb
Interactive cloning with the S ...... clic nucleotide-gated channels
@nl
P2093
P2860
P921
P3181
P356
P1476
Interactive cloning with the S ...... clic nucleotide-gated channels
@en
P2093
P2860
P304
14815-14820
P3181
P356
10.1073/PNAS.94.26.14815
P407
P50
P577
1997-12-01T00:00:00Z