Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids

Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids

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http://www.wikidata.org/entity/Q24564222

Q24564222

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Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain Male sex determination: insights into molecular mechanisms SF-1 a key player in the development and differentiation of steroidogenic tissues Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes The varied roles of nuclear receptors during vertebrate embryonic development.Differentiation of mesenchymal stem cells into gonad and adrenal steroidogenic cells Modulation of human luteinizing hormone beta gene transcription by MIP-2A Function of the transcriptional regulating protein of 132 kDa (TReP-132) on human P450scc gene expression AP-2 gamma and the homeodomain protein distal-less 3 are required for placental-specific expression of the murine 3 beta-hydroxysteroid dehydrogenase VI gene, Hsd3b6 Stage-specific inhibition of TrkB activity leads to long-lasting and sexually dimorphic effects on body weight and hypothalamic gene expression PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1 Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development.Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice Synergy of SF1 and RAR in activation of Oct-3/4 promoter NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development Steroidogenic factor 1 differentially regulates fetal and adult leydig cell development in male mice Central urocortin 3 and type 2 corticotropin-releasing factor receptor in the regulation of energy homeostasis: critical involvement of the ventromedial hypothalamus.Steroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineage Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse.Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF.Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1.Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening Minireview: Nuclear receptors, hematopoiesis, and stem cells.Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolism Genetic regulation of pituitary gland development in human and mouse Fetal Leydig cell origin and development.Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease Transgenic expression of Ad4BP/SF-1 in fetal adrenal progenitor cells leads to ectopic adrenal formation.Pituitary homeobox 2 regulates adrenal4 binding protein/steroidogenic factor-1 gene transcription in the pituitary gonadotrope through interaction with the intronic enhancer Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit.Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1 Steroid hormone receptors: evolution, ligands, and molecular basis of biologic function.Insights into the Development of the Adult Leydig Cell Lineage from Stem Leydig Cells.Regulation of cytochrome P450 (CYP) genes by nuclear receptors.Susceptible periods during embryogenesis of the heart and endocrine glands Human NR5A1/SF-1 mutations show decreased activity on BDNF (brain-derived neurotrophic factor), an important regulator of energy balance: testing impact of novel SF-1 mutations beyond steroidogenesis.Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2.Identification of a novel distal control region upstream of the human steroidogenic acute regulatory protein (StAR) gene that participates in SF-1-dependent chromatin architecture.Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells.Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway.

P2860

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P2860

Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids

Item

http://www.wikidata.org/entity/Q24564222

description

1995 nî lūn-bûn

@nan

1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1995年の論文

@ja

1995年論文

@yue

1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

@zh-mo

1995年論文

@zh-tw

1995年论文

@wuu