Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP - Test2 - elhamkhani - TriplyDB

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

http://www.wikidata.org/entity/Q24594281

about

Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover Regulation of TAZ in cancer The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair Mechanisms of Hippo pathway regulation The TEAD Family and Its Oncogenic Role in Promoting Tumorigenesis Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.The emerging molecular machinery and therapeutic targets of metastasis The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration Targeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver Fibrosis Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy YAP and TAZ: a nexus for Hippo signaling and beyond Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer Hippo/YAP pathway for targeted therapy Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression Latest developments in our understanding of the pathogenesis of mesothelioma and the design of targeted therapies Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor.The Hippo signaling pathway and translational opportunities for brain cancers The Hippo signaling pathway in stem cell biology and cancer The role of the Hippo pathway in human disease and tumorigenesis Fluid shear stress activates YAP1 to promote cancer cell motility Actomyosin contractility provokes contact inhibition in E-cadherin-ligated keratinocytes.The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells.Verteporfin exhibits YAP-independent anti-proliferative and cytotoxic effects in endometrial cancer cells The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches.Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.The Hippo pathway in disease and therapy: cancer and beyond Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst.

P2860

Q24298571-68509993-769E-4991-B378-A56F5333A1F2 Q24300770-6A1BD0C2-3FEE-4F81-BF3C-02FCE657B576 Q24303432-582809F8-BC75-4295-8488-0A5A79542C67 Q26740462-35574BF7-7013-41F8-BB2F-A7215F26FCFC Q26744308-15F256C5-DA09-46A9-B524-A04B6AB7A403 Q26771285-6280177F-21DD-43F8-A0F4-1A989391CE5E Q26775126-CC6A9E2F-1FAE-48AE-B766-115F540E79CC Q26782820-AF0D33E2-BC3B-447B-86DC-064F13491672 Q26782842-771AF6C1-4F2F-41D1-8431-4A928E872E58 Q26798420-2A40D2C7-63C7-4A10-8E5A-E569CA6433E0 Q26827810-06E39C72-D5AF-49D0-B319-1F0839956380 Q27022207-3D8844B1-79E0-419B-8A8E-C3C8D66443CD Q27025661-A60A2761-B101-41AA-8054-2A5EF5C1001D Q27727708-923C6CE0-1E70-4CB6-A242-AB96577F8BE9 Q28070012-AFC44194-5887-4C55-A5F6-8AC909B488F9 Q28078129-051196A1-0D04-433D-A26F-74D5F224EA3F Q28085636-64F8414E-8039-4731-ADE3-0622E3F83400 Q28086905-C7908A43-8F28-4E76-AD89-06EF407E9190 Q28088294-179D18EA-F955-4B3A-8FDF-54ECE28499C3 Q28269498-2A03324B-58E5-4BD8-AD2D-EC5EEA6248BE Q28291847-2767AF56-0165-46DC-9681-1100D3BAFA16 Q28395597-E43E1BF0-F29B-43B9-82D2-D1781F040ABC Q28553906-AE3E430E-BD46-4E48-81F3-C574BE3804CD Q28818447-DFF7C9C2-7CFA-48C7-A215-9B4BD8D6D8EA Q28828570-3C4EA8DD-972C-440D-A337-C73261C97C04 Q30354662-456E708E-BCBA-4BF6-81C0-496A9F2560FF Q30369861-1DD1228C-5B16-4E7E-8DFD-0C2B23A6AFFF Q30395225-910DB1EB-D4CF-4E04-B3AB-1BB7AB5362FB Q30410176-5E1F736B-3310-4B5D-9FDD-EEC104B64A20 Q30433413-0CBB8B19-BCDE-4FCD-85CA-FA9D4FDC267E Q30835797-901FB26E-063B-4596-8DDA-E3228B22178C Q30845170-EFA28421-9865-4298-BF7A-C802AE133E54 Q33676720-E6F07ED6-D54D-46C9-9270-BFB46805E47F Q33709820-D84F057B-4B38-478B-B3F2-F1D510C401EE Q33737254-4C1D19C9-02A5-4452-903C-4928C0997778 Q33751702-0CCC4C83-F9F6-4161-96B6-1BB6C39CC4BD Q33819083-E48EE57F-4E0A-4CA6-97B2-B05E936172F7 Q33937666-55B4965C-AC33-4598-973D-CCDA73E77519 Q33943271-242794F0-C129-46D0-ABDF-4A83D1FF8445 Q34098464-1D5849CA-ACF8-4167-9069-AE194893041E

P2860

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

http://www.wikidata.org/entity/Q24594281

description

2012 nî lūn-bûn

@nan

2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Genetic and pharmacological di ...... the oncogenic activity of YAP

@ast

Genetic and pharmacological di ...... the oncogenic activity of YAP

@en

Genetic and pharmacological di ...... the oncogenic activity of YAP

@nl

type

label

Genetic and pharmacological di ...... the oncogenic activity of YAP

@ast

Genetic and pharmacological di ...... the oncogenic activity of YAP

@en

Genetic and pharmacological di ...... the oncogenic activity of YAP

@nl

prefLabel

Genetic and pharmacological di ...... the oncogenic activity of YAP

@ast

Genetic and pharmacological di ...... the oncogenic activity of YAP

@en

Genetic and pharmacological di ...... the oncogenic activity of YAP

@nl

P1433

Q24594281-7F474873-2FA0-4EC7-A483-05A184A52C34

P1476

Q24594281-62F05369-C6E4-4552-BA2E-D8E1E3577CEA

P2093

Q24594281-0B652BE7-C33B-48A3-8E8D-294E6A6936C1

Q24594281-377F8009-0DC8-4A05-8578-820BF08622A5

Q24594281-467D3EAD-0EA2-44F6-8FAF-9D2EC64E7FD8

Q24594281-CD93C6B1-98C4-4049-9D20-10CBBB49EA84

Q24594281-DB9A2C9F-0BB2-4AB7-BDB8-3AAB4F7FA376

Q24594281-EE256104-72A7-486B-B868-BCBBE764FECF

P2860

Q24594281-0117E257-64C3-46D7-A3D6-26AB8EFB705B

Q24594281-0DFC6C49-F039-4EA2-83FF-2CB8966BC962

Q24594281-14A7223D-6324-4325-8EA9-0E0621C0ECB5

Q24594281-14DEA7FE-EC72-4F40-8FF8-591C7018436A

Q24594281-19A9C51A-6CB3-4DBE-AE8B-4C02BD6BF429

Q24594281-3493756D-306B-452B-9FD9-16FB7E53D504

Q24594281-53BE3B77-A11A-4A54-B8CB-2434722FB46D

Q24594281-58E3A46D-9EBB-4DBE-BFA2-2990937F72EB

Q24594281-5C20107F-B423-471C-9541-6A59BA22A346

Q24594281-63FDB285-A624-470E-95DF-37F3904F290D

P304

Q24594281-0A71A214-290B-468A-8899-BA9703A83E3E

P31

Q24594281-193C6416-41C9-436C-836B-8A493120DD22

P3181

Q24594281-97CB9D15-60D3-4BEA-AB0B-00E601DC36D9

P356

Q24594281-53DC9A9F-FCC4-48CC-86E4-4D0FCDF4FE17

P407

Q24594281-1BC39813-2213-4230-8FFF-E95D2F00352D

P433

Q24594281-5EECCD67-2DD5-465B-A336-5778A33892D3

P478

Q24594281-F3A3D38C-FC34-4C6C-85DE-4E2242ECA6BA

P50

Q24594281-38AC6BEE-5DE5-41A0-9746-536EE7666DDE

Q24594281-419C9607-358E-4112-B3DE-BFFCC4BAF0D2

P577

Q24594281-CF626C7E-8F15-4CE5-AD7D-AD83841D2E71

P5875

Q24594281-4FE7F39B-BCCF-46A3-B966-24CD66B3184F

P698

Q24594281-35D300D9-84C7-48C1-B8B2-D5DA91BFDC6F

P921

Q24594281-E9A76272-D2C5-4CAF-9892-11CA81CD07C0

P932

Q24594281-34B5027C-73BA-4774-86DE-907A9ACD8E46

P3181

P356

P1433

Genes & Development

P1476

Genetic and pharmacological di ...... the oncogenic activity of YAP

@en

P2093

Bo Huang

http://www.w3.org/2001/XMLSchema#string

Duojia Pan

http://www.w3.org/2001/XMLSchema#string

Jun O Liu

http://www.w3.org/2001/XMLSchema#string

Qian Chen

http://www.w3.org/2001/XMLSchema#string

Robert A Anders

http://www.w3.org/2001/XMLSchema#string

Se-Jin Lee

http://www.w3.org/2001/XMLSchema#string

P2860

TEAD mediates YAP-dependent gene induction and growth control

The hippo signaling pathway in development and cancer

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

Structural insights into the YAP and TEAD complex

Structural basis of YAP recognition by TEAD4 in the Hippo pathway

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

Fluorescence spectra of hematoporphyrin and hematoporphyrin-diacetate aggregates in buffer solution

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

P304

1300-5

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

691350

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.192856.112

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

26

http://www.w3.org/2001/XMLSchema#string

P50

Yi Liu-Chittenden

P577

2012-06-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

225282607

http://www.w3.org/2001/XMLSchema#string

P698

22677547

http://www.w3.org/2001/XMLSchema#string

P921

P932

3387657

http://www.w3.org/2001/XMLSchema#string