The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version - Test2 - elhamkhani - TriplyDB

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

http://www.wikidata.org/entity/Q28281214

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Whole-Genome Resequencing of Experimental Populations Reveals Polygenic Basis of Egg-Size Variation in Drosophila melanogaster Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1 Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP Tead4 is constitutively nuclear, while nuclear vs. cytoplasmic Yap distribution is regulated in preimplantation mouse embryos Structures of YAP protein domains reveal promising targets for development of new cancer drugs α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 Hippo pathway-independent restriction of TAZ and YAP by angiomotin Secreted protein kinases Regulation of TAZ in cancer G Protein-Coupled Receptors in Cancer The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials Emerging role of Hippo pathway in gastric and other gastrointestinal cancers The TEAD Family and Its Oncogenic Role in Promoting Tumorigenesis Mechanosensitive mechanisms in transcriptional regulation Mammalian Hippo signalling: a kinase network regulated by protein-protein interactions Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation Engaged for survival: From cadherin ligation to STAT3 activation Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation Comparative study of Hippo pathway genes in cellular conveyor belts of a ctenophore and a cnidarian.Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5 Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts miR-206 Mediates YAP-Induced Cardiac Hypertrophy and Survival Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1 The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα Evaluation of a partial genome screening of two asthma susceptibility regions using bayesian network based bayesian multilevel analysis of relevance Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit miR-222/VGLL4/YAP-TEAD1 regulatory loop promotes proliferation and invasion of gastric cancer cells.Regulation of localization and function of the transcriptional co-activator YAP by angiomotin.Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms.

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

http://www.wikidata.org/entity/Q28281214

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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name

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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type

label

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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prefLabel

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

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Genes & Development

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The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

@en

P2093

Bin Zhao

http://www.w3.org/2001/XMLSchema#string

Kun-Liang Guan

http://www.w3.org/2001/XMLSchema#string

Li Li

http://www.w3.org/2001/XMLSchema#string

Qunying Lei

http://www.w3.org/2001/XMLSchema#string

P2860

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

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862-74

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scholarly article

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691128

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10.1101/GAD.1909210

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9

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24

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44570347

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20439427

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2861185

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