Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin
about
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 buddingStructural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1BSpastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretionMultivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.The chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functionsNo strings attached: the ESCRT machinery in viral budding and cytokinesisThe ESCRT machinery: from the plasma membrane to endosomes and back againMembrane-shaping disorders: a common pathway in axon degenerationMicrotubule-severing enzymes at the cutting edgeDifferences in the curing of [PSI+] prion by various methods of Hsp104 inactivationQuantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective SpastinAsymmetric ring structure of Vps4 required for ESCRT-III disassembly.Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.Spastin's microtubule-binding properties and comparison to kataninBiochemical and Structural Studies of Yeast Vps4 OligomerizationA Common Substrate Recognition Mode Conserved between Katanin p60 and VPS4 Governs Microtubule Severing and Membrane Skeleton ReorganizationStructure and function of the AAA+ protein CbbX, a red-type Rubisco activaseStructure of green-type Rubisco activase from tobaccoCrystal structure of the human spastin AAA domainStructural Insights into the Unusually Strong ATPase Activity of the AAA Domain of the Caenorhabditis elegans Fidgetin-like 1 (FIGL-1) ProteinThe Oligomeric State of the Active Vps4 AAA ATPaseHereditary spastic paraplegia SPG4: what is known and not known about the disease.Structural and functional characterization of the microtubule interacting and trafficking domains of two oomycete chitin synthasesTargeting Microtubules for Wound RepairThe nucleotide cycle of spastin correlates with its microtubule-binding propertiesTubulin polyglutamylation stimulates spastin-mediated microtubule severingThe non-catalytic domains of Drosophila katanin regulate its abundance and microtubule-disassembly activityExploring the contribution of collective motions to the dynamics of forced-unfolding in tubulin.Proteolysis-Dependent Remodeling of the Tubulin Homolog FtsZ at the Division Septum in Escherichia coli.Probing the origin of tubulin rigidity with molecular simulations.Functional conservation of human Spastin in a Drosophila model of autosomal dominant-hereditary spastic paraplegiaMicrotubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formationEngineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane.Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respirationHyperglutamylation of tubulin can either stabilize or destabilize microtubules in the same cell.Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegiaMicrotubule-severing enzymes.Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms.
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P248
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P2860
Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural basis of microtubul ...... tic paraplegia protein spastin
@ast
Structural basis of microtubul ...... tic paraplegia protein spastin
@en
Structural basis of microtubul ...... tic paraplegia protein spastin
@nl
type
label
Structural basis of microtubul ...... tic paraplegia protein spastin
@ast
Structural basis of microtubul ...... tic paraplegia protein spastin
@en
Structural basis of microtubul ...... tic paraplegia protein spastin
@nl
prefLabel
Structural basis of microtubul ...... tic paraplegia protein spastin
@ast
Structural basis of microtubul ...... tic paraplegia protein spastin
@en
Structural basis of microtubul ...... tic paraplegia protein spastin
@nl
P2860
P3181
P356
P1433
P1476
Structural basis of microtubul ...... tic paraplegia protein spastin
@en
P2093
Ronald D Vale
P2860
P2888
P3181
P356
10.1038/NATURE06482
P407
P577
2008-01-17T00:00:00Z
P5875
P6179
1029072052