Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks - Test2 - elhamkhani - TriplyDB

Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks

Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks

http://www.wikidata.org/entity/Q24599990

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Aneuploidy in stem cells Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction The autoregulation of a eukaryotic DNA transposon I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin DNA damage responses in human induced pluripotent stem cells and embryonic stem cells.Mutation frequency dynamics in HPRT locus in culture-adapted human embryonic stem cells and induced pluripotent stem cells correspond to their differentiated counterparts Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells.Rad51 regulates cell cycle progression by preserving G2/M transition in mouse embryonic stem cells.Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.A miR-590/Acvr2a/Rad51b axis regulates DNA damage repair during mESC proliferation Stem cells: the pursuit of genomic stability.Mismatch and base excision repair proficiency in murine embryonic stem cells Creation of Mice Bearing a Partial Duplication of HPRT Gene Marked with a GFP Gene and Detection of Revertant Cells In Situ as GFP-Positive Somatic Cells Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels.Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability Crypt base columnar stem cells in small intestines of mice are radioresistant.Stacking the DEK: from chromatin topology to cancer stem cells.Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses.Pluripotent Stem Cells and DNA Damage Response to Ionizing Radiations.Genetic and epigenetic variations in iPSCs: potential causes and implications for application Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury.Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment.Uracil DNA glycosylase (UNG) loss enhances DNA double strand break formation in human cancer cells exposed to pemetrexed Effect of ionizing radiation on the proliferation of human embryonic stem cells.DNA double-strand breaks in human induced pluripotent stem cell reprogramming and long-term in vitro culturing Mechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cells Genome damage in induced pluripotent stem cells: assessing the mechanisms and their consequences.Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease.Targeted mutagenesis tools for modelling psychiatric disorders.Quality control: Genome maintenance in pluripotent stem cells.Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells.The concept of radiation-enhanced stem cell differentiation mESC-based in vitro differentiation models to study vascular response and functionality following genotoxic insults.DNA repair mechanisms in embryonic stem cells.Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation.Capturing Human Naïve Pluripotency in the Embryo and in the Dish.

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P2860

Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks

http://www.wikidata.org/entity/Q24599990

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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type

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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prefLabel

Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Stem Cells and Development

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Mouse embryonic stem cells, bu ...... epair double-strand DNA breaks

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Elisia D Tichy

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George F Babcock

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Li Deng

http://www.w3.org/2001/XMLSchema#string

Li Liang

http://www.w3.org/2001/XMLSchema#string

Peter J Stambrook

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Resmi Pillai

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Sandy J Schwemberger

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P2860

Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase

Embryonic stem cells and somatic cells differ in mutation frequency and type

Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system

Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

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1699-711

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scholarly article

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2436827

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10.1089/SCD.2010.0058

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11

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19

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Jay A. Tischfield

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2010-11-01T00:00:00Z

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44577331

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20446816

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