Frequent mutation of BAP1 in metastasizing uveal melanomas - Test2 - elhamkhani - TriplyDB

Frequent mutation of BAP1 in metastasizing uveal melanomas

Frequent mutation of BAP1 in metastasizing uveal melanomas

http://www.wikidata.org/entity/Q24601069

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EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation High incidence of somatic BAP1 alterations in sporadic malignant mesothelioma ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex BAP1 is phosphorylated at serine 592 in S-phase following DNA damage Germline mutations in BAP1 predispose to melanocytic tumors Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma Germline BAP1 mutations predispose to malignant mesothelioma Metastatic disease from uveal melanoma: treatment options and future prospects Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment Uveal melanoma as a target for immune-therapy Uveal Melanoma Patient-Derived Xenografts Drosophila as a Potential Model for Ocular Tumors Culturing Uveal Melanoma Cells Novel Insights into the Role of Long Noncoding RNA in Ocular Diseases Upcoming translational challenges for uveal melanoma Update in genetic susceptibility in melanoma Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work Cross-species models of human melanoma An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma Recent developments in prognostic and predictive testing in uveal melanoma From human genome to cancer genome: the first decade Pathways and therapeutic targets in melanoma Emerging patterns of somatic mutations in cancer Metastatic uveal melanoma: biology and emerging treatments Uveal melanoma cells utilize a novel route for transendothelial migration Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation.Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators BAP1 and SETD2: a report by MSKCC and the KIRC TCGA research network Prognostic parameters in uveal melanoma and their association with BAP1 expression.Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors.The genetics of uveal melanoma: current insights Uveal Melanoma: Current Trends in Diagnosis and Management The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer Connecting molecular pathways to hereditary cancer risk syndromes Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma An asbestos-exposed family with multiple cases of pleural malignant mesothelioma without inheritance of a predisposing BAP1 mutation Germline BAP1 mutation in a family with high incidence of multiple primary cancers and a potential gene-environment interaction Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma Comprehensive review of BAP1 tumor predisposition syndrome with report of two new cases

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Frequent mutation of BAP1 in metastasizing uveal melanomas

http://www.wikidata.org/entity/Q24601069

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Frequent mutation of BAP1 in metastasizing uveal melanomas

@ast

Frequent mutation of BAP1 in metastasizing uveal melanomas

@en

Frequent mutation of BAP1 in metastasizing uveal melanomas

@nl

type

label

Frequent mutation of BAP1 in metastasizing uveal melanomas

@ast

Frequent mutation of BAP1 in metastasizing uveal melanomas

@en

Frequent mutation of BAP1 in metastasizing uveal melanomas

@nl

prefLabel

Frequent mutation of BAP1 in metastasizing uveal melanomas

@ast

Frequent mutation of BAP1 in metastasizing uveal melanomas

@en

Frequent mutation of BAP1 in metastasizing uveal melanomas

@nl

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SCIENCE.1194472

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Frequent mutation of BAP1 in metastasizing uveal melanomas

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Cynthia Helms

http://www.w3.org/2001/XMLSchema#string

J William Harbour

http://www.w3.org/2001/XMLSchema#string

Katie A Matatall

http://www.w3.org/2001/XMLSchema#string

Li Cao

http://www.w3.org/2001/XMLSchema#string

Lori A Worley

http://www.w3.org/2001/XMLSchema#string

M Laurin Council

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Shenghui Duan

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P2860

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.

Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1

Exome sequencing identifies the cause of a mendelian disorder

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

Oncogenic mutations in GNAQ occur early in uveal melanoma

A genetic screen identifies novel polycomb group genes in Drosophila

The genomic landscapes of human breast and colorectal cancers

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scholarly article

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374586

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10.1126/SCIENCE.1194472

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P433

6009

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330

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Anne M. Bowcock

Elisha Roberson

Michael D Onken

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2010-12-03T00:00:00Z

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47679174

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21051595

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3087380

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