Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag
about
Click chemistry in complex mixtures: bioorthogonal bioconjugationSite-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 2: Peptide Tags and Unnatural Amino AcidsWorld Antibody-Drug Conjugate Summit, October 15-16, 2013, San Francisco, CA.Tailoring chimeric ligands for studying and biasing ErbB receptor family interactionsEngineering protein farnesyltransferase for enzymatic protein labeling applications.Synthesis of bispecific antibodies using genetically encoded unnatural amino acids.A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteinsSite-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug developmentSynthesis of non-linear protein dimers through a genetically encoded Thiol-ene reaction.Methods to Make Homogenous Antibody Drug Conjugates.Homogeneous bispecifics by disulfide bridging.Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers.Preparation of unnatural N-to-N and C-to-C protein fusionsSNaPe: a versatile method to generate multiplexed protein fusions using synthetic linker peptides for in vitro applications.Molecular imaging of biological systems with a clickable dye in the broad 800- to 1,700-nm near-infrared windowSite-specific chemical protein conjugation using genetically encoded aldehyde tagsFormylbenzene diazonium hexafluorophosphate reagent for tyrosine-selective modification of proteins and the introduction of a bioorthogonal aldehyde.A Pictet-Spengler ligation for protein chemical modificationStreamlined expressed protein ligation using split inteins.Simultaneous Site-Specific Dual Protein Labeling Using Protein Prenyltransferases.Precision glycocalyx editing as a strategy for cancer immunotherapy.Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer.Lighting the path: photopatternable substrates for biological applications."Click" reactions: a versatile toolbox for the synthesis of peptide-conjugates.Selective chemical protein modification.Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.A modular approach for assembling aldehyde-tagged proteins on DNA scaffolds.Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry.Chemical Protein Modification through Cysteine.Towards the next generation of biomedicines by site-selective conjugation.Emerging site-specific bioconjugation strategies for radioimmunotracer development.Site-selective incorporation and ligation of protein aldehydes.Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms.Acylboranes: synthetic strategies and applications.Chemoenzymatic Fc glycosylation via engineered aldehyde tags.Triazol-substituted titanocenes by strain-driven 1,3-dipolar cycloadditionsSimultaneous dual protein labeling using a triorthogonal reagent.Alkyne phosphonites for sequential azide-azide couplings.A highly efficient oxidative condensation reaction for selective protein conjugation.Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation.
P2860
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P2860
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@ast
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@en
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@nl
type
label
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@ast
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@en
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@nl
prefLabel
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@ast
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@en
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@nl
P2093
P2860
P50
P356
P1476
Synthesis of heterobifunctiona ...... chemistry and the aldehyde tag
@en
P2093
Carolyn R Bertozzi
Gregory W de Hart
Jason E Hudak
Robyn M Barfield
P2860
P304
P356
10.1002/ANIE.201108130
P407
P577
2012-04-23T00:00:00Z