Chemoenzymatic Fc glycosylation via engineered aldehyde tags. - Test2 - elhamkhani - TriplyDB

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

http://www.wikidata.org/entity/Q39061546

about

Intramolecular N-glycan/polypeptide interactions observed at multiple N-glycan remodeling steps through [(13)C,(15)N]-N-acetylglucosamine labeling of immunoglobulin G1.Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development Bacterial glycosidases in pathogenesis and glycoengineering.Methods to Make Homogenous Antibody Drug Conjugates.Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension.Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.Protein-polymer therapeutics: a macromolecular perspective.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.Peptide-tags for site-specific protein labelling in vitro and in vivo.Structurally Defined αMHC-II Nanobody-Drug Conjugates: A Therapeutic and Imaging System for B-Cell Lymphoma.Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates.Site-selective incorporation and ligation of protein aldehydes.Designing sugar mimetics: non-natural pyranosides as innovative chemical tools.N-O linkage in carbohydrates and glycoconjugates.Piperidine-based glycodendrons as protein N-glycan prosthetics.Improving theranostics in pancreatic cancer.Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements.Mutation of Conserved Residues Increases in Vitro Activity of the Formylglycine-Generating Enzyme.Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme.One-Step Derivatization of Reducing Oligosaccharides for Rapid and Live-Cell-Compatible Chelation-Assisted CuAAC Conjugation.In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I).Synthetic and semi-synthetic approaches to unprotected N-glycan oxazolines.

P2860

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P2860

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

http://www.wikidata.org/entity/Q39061546

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

@en

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

@nl

type

label

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

@en

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

@nl

prefLabel

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

@en

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

@nl

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P1433

Bioconjugate Chemistry

P1476

Chemoenzymatic Fc glycosylation via engineered aldehyde tags

@en

P2093

Anthony T Iavarone

http://www.w3.org/2001/XMLSchema#string

Elizabeth L Smith

http://www.w3.org/2001/XMLSchema#string

Kamil Godula

http://www.w3.org/2001/XMLSchema#string

Lai-Xi Wang

http://www.w3.org/2001/XMLSchema#string

P2860

A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme.

Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

Function and Structure of a Prokaryotic Formylglycine-generating Enzyme

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

Introducing genetically encoded aldehydes into proteins

EndoS, a novel secreted protein from Streptococcus pyogenes with endoglycosidase activity on human IgG

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme

Fcgamma receptors as regulators of immune responses

Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity.

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788-795

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scholarly article

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10.1021/BC500061S

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4

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25

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Carolyn Bertozzi

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2014-04-07T00:00:00Z

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261405312

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24702330

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4004622

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