The roles of PARP1 in gene control and cell differentiation - Test2 - elhamkhani - TriplyDB

The roles of PARP1 in gene control and cell differentiation

The roles of PARP1 in gene control and cell differentiation

http://www.wikidata.org/entity/Q24604774

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A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development ADP-ribosyltransferases and poly ADP-ribosylation Promoter hypomethylation, especially around the E26 transformation-specific motif, and increased expression of poly (ADP-ribose) polymerase 1 in BRCA-mutated serous ovarian cancer Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture Regulation of myofibroblast differentiation by poly(ADP-ribose) polymerase 1 Dynamic chromatin accessibility modeled by Markov process of randomly-moving molecules in the 3D genome Targeting microglial activation in stroke therapy: pharmacological tools and gender effects.Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner Family-wide analysis of poly(ADP-ribose) polymerase activity New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Poly(ADP-Ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines.Poly(ADP-ribosyl)ation acts in the DNA demethylation of mouse primordial germ cells also with DNA damage-independent roles.Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation PARP-1 modulates amyloid beta peptide-induced neuronal damage.SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress.Noncovalent pADPr interaction with proteins and competition with RNA for binding to proteins.Lidocaine induces endoplasmic reticulum stress-associated apoptosis in vitro and in vivo.Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation.Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.Poly(ADP-Ribosyl)ation Affects Histone Acetylation and Transcription.Polymorphisms in poly (ADP-ribose) polymerase-1 (PARP1) promoter and 3' untranslated region and their association with PARP1 expression in breast cancer patients.The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1.Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2.Cytotoxic and apoptotic effects of menadione on rat hepatocellular carcinoma cells Alternative modes of binding of poly(ADP-ribose) polymerase 1 to free DNA and nucleosomes ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β Mitotic bookmarking: maintaining post-mitotic reprogramming of transcription reactivation Poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-interacting protein Hrp38 regulate pattern formation during Drosophila eye development.Post-transcriptional regulation by poly(ADP-ribosyl)ation of the RNA-binding proteins.Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver.ADP-ribosylation of histones by ARTD1: an additional module of the histone code?Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes.On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.The expanding role of PARPs in the establishment and maintenance of heterochromatin.Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response.New links between mRNA polyadenylation and diverse nuclear pathways.Deciphering the insights of poly(ADP-ribosylation) in tumor progression.Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors.FGF21 functions as a sensitive biomarker of APAP-treated patients and mice.

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The roles of PARP1 in gene control and cell differentiation

http://www.wikidata.org/entity/Q24604774

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2010 nî lūn-bûn

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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The roles of PARP1 in gene control and cell differentiation

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J.GDE.2010.06.001

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Current Opinion in Genetics & Development

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The roles of PARP1 in gene control and cell differentiation

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Alexei V Tulin

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Yingbiao Ji

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P2860

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

The histone variant macroH2A is an epigenetic regulator of key developmental genes

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli

The macro domain is an ADP-ribose binding module

Modulation of nucleosome-binding activity of FACT by poly(ADP-ribosyl)ation

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)

Poly (ADP-ribose) polymerase 1 is required for protein localization to Cajal body

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

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