Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells - Test2 - elhamkhani - TriplyDB

Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Long Noncoding RNAs as Novel Biomarkers Have a Promising Future in Cancer Diagnostics Autophagy in cancer Chloroquine binding reveals flavin redox switch function of quinone reductase 2.Chloroquine or chloroquine-PI3K/Akt pathway inhibitor combinations strongly promote γ-irradiation-induced cell death in primary stem-like glioma cells Functional analysis of a novel glioma antigen, EFTUD1.Low-dose fractionated radiotherapy and concomitant chemotherapy in glioblastoma multiforme with poor prognosis: a feasibility study.Chloroquine inhibits hepatocellular carcinoma cell growth in vitro and in vivo.Chloroquine potentiates the anti-cancer effect of lidamycin on non-small cell lung cancer cells in vitro CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin.Phase II randomized, double-blind, placebo-controlled study of whole-brain irradiation with concomitant chloroquine for brain metastases.Quercetin induces mitochondrial mediated apoptosis and protective autophagy in human glioblastoma U373MG cells Lysosomotropism depends on glucose: a chloroquine resistance mechanism Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells.Stress management by autophagy: Implications for chemoresistance.Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells.Chloroquine inhibits the malignant phenotype of glioblastoma partially by suppressing TGF-beta.Signaling of chloroquine-induced stress in the yeast Saccharomyces cerevisiae requires the Hog1 and Slt2 mitogen-activated protein kinase pathways.Suberoylanilide hydroxamic acid (SAHA) causes tumor growth slowdown and triggers autophagy in glioblastoma stem cells.Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation.Anti-inflammatory activity of chloroquine and amodiaquine through p21-mediated suppression of T cell proliferation and Th1 cell differentiation.Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase.Chloroquine inhibits tumor growth and angiogenesis in malignant pleural effusion.FET-PET-based reirradiation and chloroquine in patients with recurrent glioblastoma: first tolerability and feasibility results.p53 in malignant glioma: 20 years later and still much to learn Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.The von Hippel-Lindau tumor suppressor regulates programmed cell death 5-mediated degradation of Mdm2.Discovery of Novel Cinchona-Alkaloid-Inspired Oxazatwistane Autophagy Inhibitors.Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?Silibinin Induced Human Glioblastoma Cell Apoptosis Concomitant with Autophagy through Simultaneous Inhibition of mTOR and YAP.The function and clinical relevance of lncRNA UBE2CP3-001 in human gliomas Re-purposing Chloroquine for Glioblastoma: Potential Merits and Confounding Variables

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

http://www.wikidata.org/entity/Q24607826

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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type

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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prefLabel

Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

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Alf Giese

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Anne Rübsam

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Christoph Schmitz-Salue

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Daniel Speidel

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Ella L Kim

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Eva-Maria Bücker

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Gabriele Warnecke

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Nadine Pettkus

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Robin Wüstenberg

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Walter Schulz-Schaeffer

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P2860

Inhibition of macroautophagy triggers apoptosis

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Bacterial topoisomerase inhibitors: quinolone and pyridone antibacterial agents

Post-translational modifications and activation of p53 by genotoxic stresses

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors.

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

Therapy of glioblastoma multiforme improved by the antimutagenic chloroquine.

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389-400

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scholarly article

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2396103

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10.1093/NEUONC/NOP046

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4

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12

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42389301

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20308316

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apoptotic process

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2940600

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