DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation - Test2 - elhamkhani - TriplyDB

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

http://www.wikidata.org/entity/Q28206029

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Phosphorylation: the molecular switch of double-strand break repair Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1 DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1 SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60 Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit TAF7: a possible transcription initiation check-point regulator The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway ATM activation by ionizing radiation requires BRCA1-associated BAAT1 CtIP is required to initiate replication-dependent interstrand crosslink repair ATM-dependent phosphorylation of ATF2 is required for the DNA damage response The human DEK oncogene regulates DNA damage response signaling and repair The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor ATMIN defines an NBS1-independent pathway of ATM signalling WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity Acetyltransferase p300 regulates NBS1-mediated DNA damage response Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling SIRT1 regulates the function of the Nijmegen breakage syndrome protein Regulation of TIP60 by ATF2 modulates ATM activation CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination A role for DEAD box 1 at DNA double-strand breaks Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints Involvement of human MOF in ATM function Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage.hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2 Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation Multiple roles of ATM in monitoring and maintaining DNA integrity Shelterin complex and associated factors at human telomeres Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells Alternative cyclin D1 splice forms differentially regulate the DNA damage response Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

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P2860

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

http://www.wikidata.org/entity/Q28206029

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

DNA damage activates ATM throu ...... ylation and dimer dissociation

@ast

DNA damage activates ATM throu ...... ylation and dimer dissociation

@en

DNA damage activates ATM throu ...... ylation and dimer dissociation

@nl

type

label

DNA damage activates ATM throu ...... ylation and dimer dissociation

@ast

DNA damage activates ATM throu ...... ylation and dimer dissociation

@en

DNA damage activates ATM throu ...... ylation and dimer dissociation

@nl

prefLabel

DNA damage activates ATM throu ...... ylation and dimer dissociation

@ast

DNA damage activates ATM throu ...... ylation and dimer dissociation

@en

DNA damage activates ATM throu ...... ylation and dimer dissociation

@nl

P1433

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P2860

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DNA damage activates ATM throu ...... ylation and dimer dissociation

@en

P2093

Christopher J Bakkenist

http://www.w3.org/2001/XMLSchema#string

Michael B Kastan

http://www.w3.org/2001/XMLSchema#string

P2860

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

Substrate specificities and identification of putative substrates of ATM kinase family members

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

The many substrates and functions of ATM

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499-506

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scholarly article

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1230217

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10.1038/NATURE01368

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6922

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421

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2003-01-30T00:00:00Z

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10926392

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1002815475

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12556884

http://www.w3.org/2001/XMLSchema#string

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