Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain - Test2 - elhamkhani - TriplyDB

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

http://www.wikidata.org/entity/Q24609907

about

Update on the Kelch-like (KLHL) gene family The involvement of a polyphenol-rich extract of black chokeberry in oxidative stress on experimental arterial hypertension Sulforaphane as a potential protective phytochemical against neurodegenerative diseases A molecular marker of artemisinin-resistant Plasmodium falciparum malaria Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)Chemoprotection by phenolic antioxidants Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2 Role of Nrf2 in oxidative stress and toxicity Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation The endoplasmic reticulum stress response in aging and age-related diseases Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway Ubiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutation Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level Molecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-association The GI-GPx gene is a target for Nrf2 Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2 Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling Cysteine-based regulation of the CUL3 adaptor protein Keap1 The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity Advances in mechanisms of anti-oxidation

P2860

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P2860

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

http://www.wikidata.org/entity/Q24609907

description

1999 nî lūn-bûn

@nan

1999 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հունվարին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

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1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@ast

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@en

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@nl

type

label

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@ast

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@en

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@nl

prefLabel

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@ast

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@en

Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

@nl

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Genes & Development

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Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain

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J D Engel

http://www.w3.org/2001/XMLSchema#string

K Igarashi

http://www.w3.org/2001/XMLSchema#string

K Itoh

http://www.w3.org/2001/XMLSchema#string

M Yamamoto

http://www.w3.org/2001/XMLSchema#string

N Wakabayashi

http://www.w3.org/2001/XMLSchema#string

T Ishii

http://www.w3.org/2001/XMLSchema#string

Y Katoh

http://www.w3.org/2001/XMLSchema#string

P2860

Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

The POZ domain: a conserved protein-protein interaction motif

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

pEF-BOS, a powerful mammalian expression vector

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

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76-86

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scholarly article

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10.1101/GAD.13.1.76

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1

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13

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1999-01-01T00:00:00Z

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13402197

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9887101

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316370

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