Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
about
Update on the Kelch-like (KLHL) gene familyThe involvement of a polyphenol-rich extract of black chokeberry in oxidative stress on experimental arterial hypertensionSulforaphane as a potential protective phytochemical against neurodegenerative diseasesA molecular marker of artemisinin-resistant Plasmodium falciparum malariaInduction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)Chemoprotection by phenolic antioxidantsMolecular basis of electrophilic and oxidative defense: promises and perils of Nrf2Role of Nrf2 in oxidative stress and toxicityAccelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null miceNrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagyThe carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activationThe endoplasmic reticulum stress response in aging and age-related diseasesStructure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingDJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathwayDJ-1 induces thioredoxin 1 expression through the Nrf2 pathwayUbiquitin ligase activity of Cul3-KLHL7 protein is attenuated by autosomal dominant retinitis pigmentosa causative mutationEctodermal-neural cortex 1 down-regulates Nrf2 at the translational levelMolecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-associationThe GI-GPx gene is a target for Nrf2Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive elementSulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimerBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseKeap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathwayRepression of PML nuclear body-associated transcription by oxidative stress-activated Bach2Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.Autophagy, mitochondria and oxidative stress: cross-talk and redox signallingCysteine-based regulation of the CUL3 adaptor protein Keap1The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegenerationRole and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stressDirect interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant responsePIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive elementThe Nrf2-antioxidant response element signaling pathway and its activation by oxidative stressCancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancyNrf2 is a direct PERK substrate and effector of PERK-dependent cell survivalCellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationPhysiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activityAdvances in mechanisms of anti-oxidation
P2860
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P2860
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@ast
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@en
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@nl
type
label
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@ast
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@en
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@nl
prefLabel
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@ast
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@en
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@nl
P2093
P2860
P356
P1433
P1476
Keap1 represses nuclear activa ...... the amino-terminal Neh2 domain
@en
P2093
K Igarashi
M Yamamoto
N Wakabayashi
P2860
P356
10.1101/GAD.13.1.76
P407
P577
1999-01-01T00:00:00Z