BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase - Test2 - elhamkhani - TriplyDB

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

http://www.wikidata.org/entity/Q24558689

about

Update on the Kelch-like (KLHL) gene family Orthopoxvirus genes that mediate disease virulence and host tropism Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2 The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 Ubiquitin-dependent regulation of COPII coat size and function Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells Regulation of TIP60 by ATF2 modulates ATM activation Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level Cysteine-based regulation of the CUL3 adaptor protein Keap1 The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction Heme induces ubiquitination and degradation of the transcription factor Bach1 ROS and ROS-Mediated Cellular Signaling Antioxidant responses and cellular adjustments to oxidative stress The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases Redox control of microglial function: molecular mechanisms and functional significance Regulation of Nrf2-Mediated Phase II Detoxification and Anti-oxidant Genes Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response Novel -Propeller of the BTB-Kelch Protein Krp1 Provides a Binding Site for Lasp-1 That Is Necessary for Pseudopodial Extension Kelch proteins: emerging roles in skeletal muscle development and diseases.Nrf2 Is an Attractive Therapeutic Target for Retinal Diseases Tumor progression and the different faces of the PERK kinase Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum Mechanistic studies of the Nrf2-Keap1 signaling pathway Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice The novel arsenical Darinaparsin circumvents BRG1-dependent, HO-1-mediated cytoprotection in leukemic cells Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2 Stress-activated cap'n'collar transcription factors in aging and human disease

P2860

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P2860

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

http://www.wikidata.org/entity/Q24558689

description

2005 nî lūn-bûn

@nan

2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@ast

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@en

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@nl

type

label

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@ast

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@en

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@nl

prefLabel

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@ast

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@en

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@nl

P1433

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Q24558689-7A241458-C73C-4F85-AE03-7F476FD9C43E

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P2860

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Q24558689-39BBE0CC-06A8-4FE8-9EC8-4CAB4E26AFDD

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P356

MCB.25.1.162-171.2005

P1433

Molecular and Cellular Biology

P1476

BTB protein Keap1 targets anti ...... on by the Cullin 3-Roc1 ligase

@en

P2093

Manabu Furukawa

http://www.w3.org/2001/XMLSchema#string

Yue Xiong

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of the BTB domain from PLZF

SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1

P304

162-71

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scholarly article

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1344290

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P356

10.1128/MCB.25.1.162-171.2005

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P433

1

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25

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2005-01-01T00:00:00Z

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P698

15601839

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P921

Nuclear factor, erythroid 2 like 2

Kelch like ECH associated protein 1

protein ubiquitination

P932

538799

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