A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease
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Genetics of coronary artery diseaseUnderstanding the genetics of coronary artery disease through the lens of noninvasive imagingPrediction of Causal Candidate Genes in Coronary Artery Disease LociGenetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasetsLarge-scale gene-centric analysis identifies novel variants for coronary artery diseaseSingle nucleotide polymorphisms in an intergenic chromosome 2q region associated with tissue factor pathway inhibitor plasma levels and venous thromboembolism.Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke?Mapping Novel Pathways in Cardiovascular Disease Using eQTL Data: The Past, Present, and Future of Gene Expression AnalysisExploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.Coronary Artery Disease-Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes.Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophagesInduction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelaeGenetics of human cardiovascular diseaseLinking disease associations with regulatory information in the human genome.Differential microRNA response to a high-cholesterol, high-fat diet in livers of low and high LDL-C baboons.Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismAssociation of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: the Athero Gene study.Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.Single nucleotide polymorphisms within LIPA (Lysosomal Acid Lipase A) gene are associated with susceptibility to premature coronary artery disease. a replication in the genetic of atherosclerotic disease (GEA) Mexican study.Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure ProgramThe ophthalmic branch of the Gutenberg Health Study: study design, cohort profile and self-reported diseasesLipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding.A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.Current genomics in cardiovascular medicineIntegrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.Identification of shared genetic susceptibility locus for coronary artery disease, type 2 diabetes and obesity: a meta-analysis of genome-wide studies.Integrative genomics in cardiovascular medicineWeighted gene co-expression network analysis identifies specific modules and hub genes related to coronary artery disease.Physiological difference in autophagic flux in macrophages from 2 mouse strains regulates cholesterol ester metabolismNext steps in cardiovascular disease genomic research--sequencing, epigenetics, and transcriptomicsFrom Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary DiseaseFrequency of the cholesteryl ester storage disease common LIPA E8SJM mutation (c.894G>A) in various racial and ethnic groups.Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.Thrombotic antiphospholipid syndrome shows strong haplotypic association with SH2B3-ATXN2 locus.Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study.Adaptive linear rank tests for eQTL studies.Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis.
P2860
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P2860
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A genome-wide association stud ...... ne for coronary artery disease
@ast
A genome-wide association stud ...... ne for coronary artery disease
@en
A genome-wide association stud ...... ne for coronary artery disease
@en-gb
A genome-wide association stud ...... ne for coronary artery disease
@nl
type
label
A genome-wide association stud ...... ne for coronary artery disease
@ast
A genome-wide association stud ...... ne for coronary artery disease
@en
A genome-wide association stud ...... ne for coronary artery disease
@en-gb
A genome-wide association stud ...... ne for coronary artery disease
@nl
prefLabel
A genome-wide association stud ...... ne for coronary artery disease
@ast
A genome-wide association stud ...... ne for coronary artery disease
@en
A genome-wide association stud ...... ne for coronary artery disease
@en-gb
A genome-wide association stud ...... ne for coronary artery disease
@nl
P2093
P2860
P50
P3181
P1476
A genome-wide association stud ...... ne for coronary artery disease
@en
P2093
Alun Evans
Arne S Schäfer
Arne Schillert
Carole Proust
Christoph Bickel
Christoph R Sinning
Christopher J O'Donnell
Daniel J Rader
Diana Rubin
Dominique Arveiler
P2860
P304
P3181
P356
10.1161/CIRCGENETICS.110.958728
P407
P50
P5008
P577
2011-08-01T00:00:00Z