Genome-environment interactions that modulate aging: powerful targets for drug discovery - Test2 - elhamkhani - TriplyDB

Genome-environment interactions that modulate aging: powerful targets for drug discovery

Genome-environment interactions that modulate aging: powerful targets for drug discovery

http://www.wikidata.org/entity/Q24615803

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Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review The role of DNA methylation in aging, rejuvenation, and age-related disease Parkinson's disease as a result of aging The hallmarks of aging Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases Evolutionary ecology of aging: time to reconcile field and laboratory research Caloric restriction, caloric restriction mimetics, and healthy aging in Okinawa: controversies and clinical implications.Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet Systematic analysis of the gerontome reveals links between aging and age-related diseases.Optimal nutrition and the ever-changing dietary landscape: a conference report.Glycerol extends lifespan of Brachionus manjavacas (Rotifera) and protects against stressors The essential role of FoxO6 phosphorylation in aging and calorie restriction.Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing.The scientific quest for lasting youth: prospects for curing aging.Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes.Bitter taste receptor polymorphisms and human aging Being cool: how body temperature influences ageing and longevity.Protein biogenesis machinery is a driver of replicative aging in yeast Rotifers as experimental tools for investigating aging.Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research Rejuvenation of gene expression pattern of aged human skin by broadband light treatment: a pilot study.A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans.Moderately lower temperatures greatly extend the lifespan of Brachionus manjavacas (Rotifera): Thermodynamics or gene regulation?Fish oil supplements, longevity and aging Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera).Serotonin: from top to bottom.Epigenomics and the regulation of aging.FOXO in aging: did evolutionary diversification of FOXO function distract it from prolonging life?Synopsis on the linkage of Alzheimer's and Parkinson's disease with chronic diseases.Machine learning for predicting lifespan-extending chemical compounds Mathematical modelling of metabolic regulation in aging.Age-Related Changes in Locomotor Performance Reveal a Similar Pattern for Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens.A synopsis on aging-Theories, mechanisms and future prospects.The DrugAge database of aging-related drugs Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.Aging-modulating treatments: from reductionism to a system-oriented perspective.Osh6 links yeast vacuolar functions to lifespan extension and TOR.Human Ageing Genomic Resources: new and updated databases.Energy restriction combined with dipeptidyl peptidase-4 inhibitor exerts neuroprotection in obese male rats.Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way.

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P2860

Genome-environment interactions that modulate aging: powerful targets for drug discovery

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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Pharmacological Reviews

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Genome-environment interactions that modulate aging: powerful targets for drug discovery

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P2093

Chintan Vora

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Daniel Wuttke

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João Pedro de Magalhães

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Michael Plank

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Shona H Wood

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P2860

The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases

The genetics of human longevity

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

The TOR pathway comes of age

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

Extending healthy life span--from yeast to humans

Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions

Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans

SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

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22090473

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3250080

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