Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
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A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in miceDouble strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG islandSIRT2 as a Therapeutic Target for Age-Related DisordersSIRT1 negatively regulates the mammalian target of rapamycinMechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress?Epigenetic regulation of caloric restriction in agingThe flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylasesJNK1 phosphorylates SIRT1 and promotes its enzymatic activityBrown remodeling of white adipose tissue by SirT1-dependent deacetylation of PparĪ³SIRT2 induces the checkpoint kinase BubR1 to increase lifespanPhosphorylation of HuR by Chk2 regulates SIRT1 expressionRegulation of unfolded protein response modulator XBP1s by acetylation and deacetylationRegulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylationSIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stabilityInhibition of SUV39H1 methyltransferase activity by DBC1Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteinsA high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexA role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagySIRT1 deacetylates APE1 and regulates cellular base excision repairReciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cellsDeacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradationInvolvement of SIRT7 in resumption of rDNA transcription at the exit from mitosisMST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylationCK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damagehSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damageCalorie restriction induces mitochondrial biogenesis and bioenergetic efficiencyCPLA 1.0: an integrated database of protein lysine acetylationHypoxic regulation of erythropoiesis and iron metabolismGenome-environment interactions that modulate aging: powerful targets for drug discoverySRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetesThe neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodiesCalorie restriction and the exercise of chromatinSIRT6 in DNA repair, metabolism and ageingPCAF acetylates {beta}-catenin and improves its stabilityp53 acetylation is crucial for its transcription-independent proapoptotic functionsNuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?SIRT1 regulates HIV transcription via Tat deacetylationExperimental study of the function of the excreted/secreted Leishmania LmSIR2 protein by heterologous expression in eukaryotic cell line
P2860
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P2860
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
description
2004 nĆ® lÅ«n-bĆ»n
@nan
2004 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
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@hyw
2004 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¬Õ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2004幓ć®č«ę
@ja
2004幓č«ę
@yue
2004幓č«ę
@zh-hant
2004幓č«ę
@zh-hk
2004幓č«ę
@zh-mo
2004幓č«ę
@zh-tw
2004幓č®ŗę
@wuu
name
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@ast
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en-gb
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@nl
type
label
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@ast
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en-gb
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@nl
prefLabel
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@ast
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en-gb
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@nl
P2093
P50
P3181
P356
P1433
P1476
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
@en
P2093
Brian Hekking
Christine Miller
Haim Y Cohen
Kevin J Bitterman
Konrad T Howitz
P3181
P356
10.1126/SCIENCE.1099196
P407
P577
2004-07-16T00:00:00Z