Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence - Test2 - elhamkhani - TriplyDB

Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

http://www.wikidata.org/entity/Q24617053

about

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy Phagocyte responses to protozoan infection and how Toxoplasma gondii meets the challenge Immune response and immunopathology during toxoplasmosis Reduced parasite motility and micronemal protein secretion by a p38 MAPK inhibitor leads to a severe impairment of cell invasion by the apicomplexan parasite Eimeria tenella Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18 Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen The Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growth Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread.The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9.ROP18 is a key factor responsible for virulence difference between Toxoplasma gondii and Neospora caninum.Toxoplasma's arms race with the host interferon response: a ménage à trois of ROPs.The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Modulation of innate immunity by Toxoplasma gondii virulence effectors.Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.Toxoplasma gondii development of its replicative niche: in its host cell and beyond.Interferon-inducible effector mechanisms in cell-autonomous immunity.Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-γ Geographic separation of domestic and wild strains of Toxoplasma gondii in French Guiana correlates with a monomorphic version of chromosome1a.Partial protective effect of intranasal immunization with recombinant Toxoplasma gondii rhoptry protein 17 against toxoplasmosis in mice The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases.Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses Subversion of host cellular functions by the apicomplexan parasites.The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.Production, characterization and applications for Toxoplasma gondii-specific polyclonal chicken egg yolk immunoglobulins.Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases.Parasites paralyze cellular host defense system to promote virulence.Genome wide in silico analysis of Plasmodium falciparum phosphatome.

P2860

Q21090491-A047817C-6A8D-45E1-A075-1D531BBCA78F Q22255519-A00B997B-F238-4776-B06C-27EFB13E882C Q24612341-E8BD34BC-999A-44BA-9A30-AEDEA53A3269 Q27317304-51A09635-9277-48B9-9E7B-88E862AA0F21 Q27321401-249DFC08-628E-4EE9-9CCE-21D8C8D18B61 Q27341809-89A1ED73-7452-4503-BC93-C90A6EDE8FCD Q27680375-3C29F157-6741-484C-8173-61FE5F8A4578 Q28476607-F4A6F1A0-2B13-466B-B4D2-C64BC6AE6318 Q28481222-EB64435B-C0B3-4DA7-9B23-D4172EB98F64 Q28482496-DDD4E568-80AE-4551-82AB-5E4AB6BBC2A7 Q28545027-1EE10283-57C6-46AE-909D-E6C19B74D489 Q28728385-2F05BE64-65AC-43A9-9600-4BA6ED3EB1E0 Q28829229-CE2B58A0-BBB5-4534-8F80-2D697D017C57 Q30042719-B5DB648D-E7E5-4BF1-9B83-7E557D77A656 Q30397112-3ADB1D12-1A2D-45CE-826E-C263D517D072 Q30540134-8FE9EC6C-D84E-4431-9995-9E3672B0EAAD Q31148891-62BBAB07-3F81-4310-915E-0340415CBAA4 Q31156269-87EDCD31-7681-4038-8CAD-ACE4076C1D84 Q33602978-5C1127A2-9D24-4B80-B0E8-0ECEDEA21604 Q33648073-AA56F989-5DC3-43AD-B1B1-E5953C99C0A0 Q33753887-83E063E0-F6A9-4767-8705-74F0875B9900 Q33851526-9E7990FC-024F-40C4-BD1E-6C9BB6478402 Q33861156-CE19C069-5F9D-49CE-B969-0DBDF94AF703 Q33899190-2920D643-1303-450B-AAA5-5361AEE51F0E Q33940781-BFB6E9ED-35B6-49A5-883A-F74CFBDB795C Q34033981-31BF55F1-B6BD-403B-A6E5-AEAFB7CCC18D Q34056304-319E7E92-EAAB-4795-ADE2-0F31AEA7DBE7 Q34057241-CEF96B64-0FBA-40B5-BF9F-9E71DFEEDF41 Q34114819-1A9B927E-A7B1-486E-9408-1E16AAD1F37B Q34139953-0232D75B-C353-48D0-A884-70EF85AEE88B Q34213936-6B43A49E-7178-4CDF-AF8F-CCD9660A9E3D Q34257517-D30F9EBB-ADC1-453A-A190-7977CB0D9CB1 Q34283543-B616862B-880D-47E6-AE47-BBACDC8D8724 Q34298612-76BC52EF-3F5D-4119-A550-C6AEB7CC6A00 Q34314006-B51BF033-5229-4FB0-BC5E-5F9D23C4E0A3 Q34325516-E0CA4D9A-AB2C-4023-8ADF-478CBC2C60A7 Q34341987-35EFEFA2-58AA-4A40-A352-D8DA74AB30BA Q34425347-EF380D81-A624-44FF-A7E5-81F3FACD143A Q34470850-348AC565-591B-4DC1-B1B9-13A803416D29 Q34637025-52B00D67-F453-42F5-A3E7-BC9E5499C51B

P2860

Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

http://www.wikidata.org/entity/Q24617053

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Phosphorylation of immunity-re ...... rophage survival and virulence

@ast

Phosphorylation of immunity-re ...... rophage survival and virulence

@en

Phosphorylation of immunity-re ...... rophage survival and virulence

@nl

type

label

Phosphorylation of immunity-re ...... rophage survival and virulence

@ast

Phosphorylation of immunity-re ...... rophage survival and virulence

@en

Phosphorylation of immunity-re ...... rophage survival and virulence

@nl

prefLabel

Phosphorylation of immunity-re ...... rophage survival and virulence

@ast

Phosphorylation of immunity-re ...... rophage survival and virulence

@en

Phosphorylation of immunity-re ...... rophage survival and virulence

@nl

P1433

Q24617053-C7AE9F6C-E14B-4A76-B771-A187C75B34AD

P1476

Q24617053-A777080F-7446-461F-A153-B6BA095D2B6A

P2093

Q24617053-100FE9E3-22FB-4783-92B8-FD5E15146D3D

Q24617053-1299E0FC-8627-4F2E-8D8C-B6A390749C12

Q24617053-29C3D067-37EE-4C9A-B726-5DA35F366574

Q24617053-3B8DF190-6662-4AA5-83DE-58486B7AF117

Q24617053-3E2BF224-E4BC-4019-B0DC-B22973ED320E

Q24617053-5899DB7F-E36F-4C80-B27A-CDDD2A97097B

Q24617053-5D5037C5-40DE-4EA2-BD70-96580DD50CCC

Q24617053-6E1FDD2F-9696-457E-B937-8BEB6FB41128

Q24617053-7B5D09A0-DDED-48F3-9A3B-66AE53528D6F

Q24617053-A06064ED-E919-4547-A345-5FD0E35CE1D0

P2860

Q24617053-0055093F-092B-466E-94EE-5729D908FB94

Q24617053-0377A9AF-09DE-4A67-A656-DF52FB185799

Q24617053-04CCF96E-54B2-4996-AB3D-5512E833E63D

Q24617053-0788E743-9C5E-48D1-AC3E-DDA0DACFEEFF

Q24617053-09EC2CB4-4A1A-4A78-ACE4-6BFB3C5B8F5B

Q24617053-0E998D33-4693-483A-9930-BC838AA9E01D

Q24617053-0FB419D0-2E00-41EE-9331-92AE6BC3D9A1

Q24617053-16010748-C6DB-4C4E-90C5-E61B7DDCE8D8

Q24617053-1C511BE3-84D8-4108-A70C-1DFA0143BC49

Q24617053-1C77D834-9B85-4E12-8AE2-405EB747585A

P304

Q24617053-3939717E-AFD1-4863-A90E-74631B2C75D1

P31

Q24617053-CCC4F30B-F25C-467C-A622-4CC10D6D5E51

P3181

Q24617053-ACC526C1-9BE9-40C8-B818-D9DD690E9C08

P356

Q24617053-70660271-A513-40B2-8A0A-A568EDB85C07

P407

Q24617053-88EBC60E-E900-454F-B8F4-EC041088CDD1

P433

Q24617053-DB7CE123-A3A9-4462-AC50-EC30D663D403

P478

Q24617053-8C33129C-A732-48A1-8FB1-AF846D30D9C7

P50

Q24617053-CF414CB9-F95D-447C-B82B-52F6B7AD586E

P577

Q24617053-1213F010-739C-4FC0-BF5D-7CF592E8CF5F

P5875

Q24617053-28686D67-303A-4DD2-9467-1D2FEDBCF59A

P698

Q24617053-84E9635B-EC4C-4B47-8712-E9AA80AF43AA

P921

Q24617053-06811D10-AA92-4E11-BB8E-2C64CBB11A09

Q24617053-301EBBE7-06E1-4CE5-9603-6FDE2B0BB17C

Q24617053-96C6753F-A52A-4D4F-B0D2-7C320913C934

Q24617053-9B630BE9-F086-40EB-BB1C-70666B9553E7

P932

Q24617053-2009B862-75B5-45D1-A0F7-3A8837716F35

P3181

P356

J.CHOM.2010.11.005

P1433

Cell Host & Microbe

P1476

Phosphorylation of immunity-re ...... rophage survival and virulence

@en

P2093

Barbara A Fox

http://www.w3.org/2001/XMLSchema#string

Benjamin E Turk

http://www.w3.org/2001/XMLSchema#string

Cheryl F Lichti

http://www.w3.org/2001/XMLSchema#string

David J Bzik

http://www.w3.org/2001/XMLSchema#string

Gregory A Taylor

http://www.w3.org/2001/XMLSchema#string

Ildiko R Dunay

http://www.w3.org/2001/XMLSchema#string

Leah M Rommereim

http://www.w3.org/2001/XMLSchema#string

Michael S Behnke

http://www.w3.org/2001/XMLSchema#string

Mona Mashayekhi

http://www.w3.org/2001/XMLSchema#string

R Reid Townsend

http://www.w3.org/2001/XMLSchema#string

P2860

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.

Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

MEME: discovering and analyzing DNA and protein sequence motifs

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

Novel structural and regulatory features of rhoptry secretory kinases in Toxoplasma gondii

EMBOSS: the European Molecular Biology Open Software Suite

WebLogo: A Sequence Logo Generator

The guanine nucleotide-binding switch in three dimensions

P304

484-95

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

795073

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.CHOM.2010.11.005

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

8

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-12-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49673377

http://www.w3.org/2001/XMLSchema#string

P698

21147463

http://www.w3.org/2001/XMLSchema#string

P921

Toxoplasma gondii

phosphorylation

P932

3013631

http://www.w3.org/2001/XMLSchema#string