Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence
about
Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategyPhagocyte responses to protozoan infection and how Toxoplasma gondii meets the challengeImmune response and immunopathology during toxoplasmosisReduced parasite motility and micronemal protein secretion by a p38 MAPK inhibitor leads to a severe impairment of cell invasion by the apicomplexan parasite Eimeria tenellaDeterminants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control itThe polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute VirulencePhosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondiiA Toxoplasma gondii pseudokinase inhibits host IRG resistance proteinsThe Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cellsInduction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondiiAdmixture and recombination among Toxoplasma gondii lineages explain global genome diversityInnate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogenThe Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growthTranscriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytesMotile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread.The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune responseEfficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9.ROP18 is a key factor responsible for virulence difference between Toxoplasma gondii and Neospora caninum.Toxoplasma's arms race with the host interferon response: a ménage à trois of ROPs.The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice.TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Modulation of innate immunity by Toxoplasma gondii virulence effectors.Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.Toxoplasma gondii development of its replicative niche: in its host cell and beyond.Interferon-inducible effector mechanisms in cell-autonomous immunity.Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-γGeographic separation of domestic and wild strains of Toxoplasma gondii in French Guiana correlates with a monomorphic version of chromosome1a.Partial protective effect of intranasal immunization with recombinant Toxoplasma gondii rhoptry protein 17 against toxoplasmosis in miceThe Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases.Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responsesSubversion of host cellular functions by the apicomplexan parasites.The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.Production, characterization and applications for Toxoplasma gondii-specific polyclonal chicken egg yolk immunoglobulins.Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases.Parasites paralyze cellular host defense system to promote virulence.Genome wide in silico analysis of Plasmodium falciparum phosphatome.
P2860
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P2860
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphorylation of immunity-re ...... rophage survival and virulence
@ast
Phosphorylation of immunity-re ...... rophage survival and virulence
@en
Phosphorylation of immunity-re ...... rophage survival and virulence
@nl
type
label
Phosphorylation of immunity-re ...... rophage survival and virulence
@ast
Phosphorylation of immunity-re ...... rophage survival and virulence
@en
Phosphorylation of immunity-re ...... rophage survival and virulence
@nl
prefLabel
Phosphorylation of immunity-re ...... rophage survival and virulence
@ast
Phosphorylation of immunity-re ...... rophage survival and virulence
@en
Phosphorylation of immunity-re ...... rophage survival and virulence
@nl
P2093
P2860
P921
P3181
P1433
P1476
Phosphorylation of immunity-re ...... rophage survival and virulence
@en
P2093
Barbara A Fox
Benjamin E Turk
Cheryl F Lichti
David J Bzik
Gregory A Taylor
Ildiko R Dunay
Leah M Rommereim
Michael S Behnke
Mona Mashayekhi
R Reid Townsend
P2860
P304
P3181
P356
10.1016/J.CHOM.2010.11.005
P407
P577
2010-12-16T00:00:00Z