Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex - Test2 - elhamkhani - TriplyDB

Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex

Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex

http://www.wikidata.org/entity/Q24621192

about

The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome The business of deubiquitination - location, location, location The role of deubiquitinating enzymes in synaptic function and nervous system diseases Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila A Strategy for Modulation of Enzymes in the Ubiquitin System Regulation of endocytic sorting by ESCRT-DUB-mediated deubiquitination Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.TRE17/USP6 regulates ubiquitylation and trafficking of cargo proteins that enter cells by clathrin-independent endocytosis.Versatile roles of k63-linked ubiquitin chains in trafficking.USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin Development of inhibitors in the ubiquitination cascade.Recurrent gain-of-function USP8 mutations in Cushing's disease.ESCRT proteins: Double-edged regulators of cellular signaling.Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting.Molecular mechanisms of ubiquitin-dependent membrane traffic Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR.RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.Ubiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channel Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome UBE4B protein couples ubiquitination and sorting machineries to enable epidermal growth factor receptor (EGFR) degradation.How ubiquitin functions with ESCRTs Ubiquitin-dependent sorting in endocytosis.USP8 modulates ubiquitination of LRIG1 for Met degradation.Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases.A multifunctional protease inhibitor to regulate endolysosomal function.Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9.The Prader-Willi syndrome proteins MAGEL2 and necdin regulate leptin receptor cell surface abundance through ubiquitination pathways.The EGFR odyssey - from activation to destruction in space and time.The ESCRT-deubiquitinating enzyme USP8 in the cervical spinal cord of wild-type and Vps54-recessive (wobbler) mutant mice.Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking.Deubiquitinating Enzymes Related to Autophagy: New Therapeutic Opportunities?

P2860

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P2860

Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex

http://www.wikidata.org/entity/Q24621192

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

@wuu

name

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@ast

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@en

Regulation of epidermal growth ...... cking by the USP8·STAM complex

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type

label

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@ast

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@en

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@nl

prefLabel

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@ast

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@en

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@nl

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P356

JBC.M109.016287

P1433

Journal of Biological Chemistry

P1476

Regulation of epidermal growth ...... cking by the USP8·STAM complex

@en

P2093

Heather Schwartz

http://www.w3.org/2001/XMLSchema#string

Ilana Berlin

http://www.w3.org/2001/XMLSchema#string

Piers D Nash

http://www.w3.org/2001/XMLSchema#string

P2860

The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors

TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

STAM-AMSH interaction facilitates the deubiquitination activity in the C-terminal AMSH

UBPY: a growth-regulated human ubiquitin isopeptidase.

The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation

AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4

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34909-21

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scholarly article

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10.1074/JBC.M109.016287

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P433

45

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285

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2010-11-05T00:00:00Z

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45827522

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20736164

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P921

protein ubiquitination

P932

2966105

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