Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases - Test2 - elhamkhani - TriplyDB

Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases

Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases

http://www.wikidata.org/entity/Q26852269

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The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3 Role of E3 ubiquitin ligases in gastric cancer Development of a fluorescence polarization based high-throughput assay to identify Casitas B-lineage lymphoma RING domain regulators Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation Non-degradative Ubiquitination of Protein Kinases.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice.Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice.In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs).Pro-oncogenic Roles of HLXB9 Protein in Insulinoma Cells through Interaction with Nono Protein and Down-regulation of the c-Met Inhibitor Cblb (Casitas B-lineage Lymphoma b).Chitin-induced and CHITIN ELICITOR RECEPTOR KINASE1 (CERK1) phosphorylation-dependent endocytosis of Arabidopsis thaliana LYSIN MOTIF-CONTAINING RECEPTOR-LIKE KINASE5 (LYK5).H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b.High c-Cbl expression in gliomas is associated with tumor progression and poor prognosis Transformation of polarized epithelial cells by apical mistrafficking of epiregulin The role of E3 ubiquitin ligase Cbl proteins in β-elemene reversing multi-drug resistance of human gastric adenocarcinoma cells The chimeric ubiquitin ligase SH2-U-box inhibits the growth of imatinib-sensitive and resistant CML by targeting the native and T315I-mutant BCR-ABL Induction of Siglec-1 by Endotoxin Tolerance Suppresses the Innate Immune Response by Promoting TGF-β1 Production.Cbl-b enhances sensitivity to 5-fluorouracil via EGFR- and mitochondria-mediated pathways in gastric cancer cells.IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors.Targeting SALL4 by entinostat in lung cancer.E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis.Cbl-family proteins as regulators of cytoskeleton-dependent phenomena.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Accumulation of Deleterious Mutations on the Neo-Y Chromosome of Japan Sea Stickleback (Gasterosteus nipponicus).Differential recruitment of E3-ubiquitin ligase complexes regulates RET isoform internalization.Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene.Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor.Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis.Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.Ubiquitin ligase Cbl-b is involved in icotinib (BPI-2009H)-induced apoptosis and G1 phase arrest of EGFR mutation-positive non-small-cell lung cancer.Cbl E3 Ligase Mediates the Removal of Nectin-1 from the Surface of Herpes Simplex Virus 1-Infected Cells.An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis.

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Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases

http://www.wikidata.org/entity/Q26852269

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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type

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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prefLabel

Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

@ast

Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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J.BBAMCR.2012.10.010

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Biochimica et Biophysica Acta

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Protein tyrosine kinase regula ...... f Cbl-family ubiquitin ligases

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Benjamin Goetz

http://www.w3.org/2001/XMLSchema#string

Dan Feng

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Gloria E O Borgstahl

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Gulzar Ahmad

http://www.w3.org/2001/XMLSchema#string

Hamid Band

http://www.w3.org/2001/XMLSchema#string

Lin Dong

http://www.w3.org/2001/XMLSchema#string

Neha Zutshi

http://www.w3.org/2001/XMLSchema#string

Nicholas Palermo

http://www.w3.org/2001/XMLSchema#string

Priyanka Arya

http://www.w3.org/2001/XMLSchema#string

Sarah Scheffe

http://www.w3.org/2001/XMLSchema#string

P2860

cbl-3: a new mammalian cbl family protein

Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

Early endosomal regulation of Smad-dependent signaling in endothelial cells

Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins

Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway

Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif

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122-139

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scholarly article

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573520

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10.1016/J.BBAMCR.2012.10.010

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P433

1

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1833

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Amarnath Natarajan

Bhopal C Mohapatra

Mayumi Naramura

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2012-10-17T00:00:00Z

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232531611

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23085373

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protein ubiquitination

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3628764

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