The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings - Test2 - elhamkhani - TriplyDB

The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings

The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings

http://www.wikidata.org/entity/Q24623195

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Interventions for chronic palmoplantar pustulosis Promising new treatments for psoriasis Linking diet to acne metabolomics, inflammation, and comedogenesis: an update The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease Targeting of interleukin-17 in the treatment of psoriasis Secukinumab: A New Treatment Option for Psoriatic Arthritis Interleukin-17 inhibitors. A new era in treatment of psoriasis and other skin diseases Co-morbidity in psoriasis: mechanisms and implications for treatment.The Role of IL-17 in the Pathogenesis and Treatment of Psoriasis.TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis.The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm.IL-6 as a druggable target in psoriasis: focus on pustular variants.IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms.IL-17/Th17 pathway is activated in acne lesions Biological products for the treatment of psoriasis: therapeutic targets, pharmacodynamics and disease-drug-drug interaction implications The pathophysiological role of dendritic cell subsets in psoriasis.Commensal-dendritic-cell interaction specifies a unique protective skin immune signature Genetic Epidemiology of Psoriasis Glucocorticoid-resistant Th17 cells are selectively attenuated by cyclosporine A.Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis.Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN.Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci Chronic, not acute, skin-specific inflammation promotes thrombosis in psoriasis murine models IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients.Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice.Shikonin inhibits IFN-γ-induced K17 over-expression of HaCaT cells by interfering with STAT3 signaling.Isolation of All CD44 Transcripts in Human Epidermis and Regulation of Their Expression by Various Agents.Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris.Low-Dose IL-17 Therapy Prevents and Reverses Diabetic Nephropathy, Metabolic Syndrome, and Associated Organ Fibrosis.The role of IL-17 in vitiligo: A review Potential role of ixekizumab in the treatment of moderate-to-severe plaque psoriasis Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques.Influence of different types of contact hypersensitivity on imiquimod-induced psoriasis-like inflammation in mice Immunity to infection in IL-17-deficient mice and humans Secukinumab, a novel anti-IL-17A antibody, shows low immunogenicity potential in human in vitro assays comparable to other marketed biotherapeutics with low clinical immunogenicity.Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes.Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy: Observations with Oral Acitretin.Norepinephrine and adenosine-5'-triphosphate synergize in inducing IL-6 production by human dermal microvascular endothelial cells.

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The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings

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David A Martin

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P2860

Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

Molecular characterization of the human interleukin (IL)-17 receptor

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Fate mapping of IL-17-producing T cells in inflammatory responses

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

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10.1038/JID.2012.194

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