High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance
about
Integrated analysis of DNA methylation, immunohistochemistry and mRNA expression, data identifies a methylation expression index (MEI) robustly associated with survival of ER-positive breast cancer patients.FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer.TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1.A first-in-human phase I, dose-escalation, multicentre study of HSP990 administered orally in adult patients with advanced solid malignancies.Research resource: enhanced genome-wide occupancy of estrogen receptor α by the cochaperone p23 in breast cancer cellsThe co-chaperone p23 promotes prostate cancer motility and metastasisThe mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives.Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis.The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarkerAilanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141.Molecular cochaperones: tumor growth and cancer treatment.Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges.Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancerAGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway.Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells.Global functional map of the p23 molecular chaperone reveals an extensive cellular network.Elevated levels of ribosomal proteins eL36 and eL42 control expression of Hsp90 in rhabdomyosarcoma.Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming.An integrated approach identifies new oncotargets in melanoma.Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma.
P2860
Q30910707-D355C561-3625-45EA-8D7D-E83E9129DB5BQ33787365-27AC5579-3641-4B58-81FD-227AB53D1FCCQ34654685-FDB6F4CB-F2E5-41E3-876C-711B444C17CDQ35098333-0C1DC94F-53EC-4D65-9687-9D198663C1C3Q35640704-00EDA0D7-AB51-4279-BF7D-6770FFBD804FQ35876533-C55BB0FA-D488-47A3-916C-D5AFD1C05B62Q35876952-FE558776-69A6-4719-B934-BA598C8EB536Q36666275-D5A2D6C1-6850-4B0D-AA3B-2CD6A0746AB9Q36903188-8A731567-C020-4411-BAB0-00FBEC9C16C4Q37508596-3100E0BC-06F6-48E2-A988-6621D9669CE2Q37745985-4A538507-2509-4F9B-B1AA-2E80462060FBQ38166376-4B0B05A0-79EE-4617-822E-71FDE60A800EQ38976702-7302E3DD-F80A-4E60-880A-932BDED11A9DQ39296019-764D4742-B1A4-4154-AF0A-D66CEFEFA315Q40143097-D61A9D1E-646A-47E1-9222-0CD74BD93FB6Q41701809-2B3E2FCC-9D78-4EB8-BE35-BB64B49D432DQ41952888-A3FF3914-3CC4-446C-890B-7B8D72DF9A5FQ42346113-0C30B080-7D00-4D55-984F-8F79BF961726Q47263046-7A39FFB9-33AC-4FAA-9F4B-ABD1A63F7EB4Q52653021-002316E8-538A-4941-9DCC-363DBE3156C3Q55461027-0EDBB15C-D7CC-41BB-A5C5-1BB604925018
P2860
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
High levels of Hsp90 cochapero ...... metastases and drug resistance
@ast
High levels of Hsp90 cochapero ...... metastases and drug resistance
@en
High levels of Hsp90 cochapero ...... metastases and drug resistance
@nl
type
label
High levels of Hsp90 cochapero ...... metastases and drug resistance
@ast
High levels of Hsp90 cochapero ...... metastases and drug resistance
@en
High levels of Hsp90 cochapero ...... metastases and drug resistance
@nl
prefLabel
High levels of Hsp90 cochapero ...... metastases and drug resistance
@ast
High levels of Hsp90 cochapero ...... metastases and drug resistance
@en
High levels of Hsp90 cochapero ...... metastases and drug resistance
@nl
P2093
P2860
P1433
P1476
High levels of Hsp90 cochapero ...... metastases and drug resistance
@en
P2093
Ellinor Oxelmark
Fernando Augusto Soares
Judith D Goldberg
Luiz Fernando Lima Reiz
Michael J Garabedian
Natalie E Simpson
Renecia Watkins
Rezina Arju
Robert J Schneider
S Joseph Huang
P2860
P304
P356
10.1158/0008-5472.CAN-10-1590
P407
P577
2010-11-01T00:00:00Z