Mutations in GNA11 in uveal melanoma - Test2 - elhamkhani - TriplyDB

Mutations in GNA11 in uveal melanoma

Mutations in GNA11 in uveal melanoma

http://www.wikidata.org/entity/Q24625723

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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP Germline mutations in BAP1 predispose to melanocytic tumors Network of Cancer Genes (NCG 3.0): integration and analysis of genetic and network properties of cancer genes Metastatic disease from uveal melanoma: treatment options and future prospects Resistant mechanisms to BRAF inhibitors in melanoma Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment Animal Models of Uveal Melanoma: Methods, Applicability, and Limitations Uveal melanoma as a target for immune-therapy Animal Eye Models for Uveal Melanoma Uveal Melanoma Patient-Derived Xenografts Drosophila as a Potential Model for Ocular Tumors Novel Insights into the Role of Long Noncoding RNA in Ocular Diseases Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)Melanoma: oncogenic drivers and the immune system Upcoming translational challenges for uveal melanoma Somatic mosaicism in the human genome Recent developments in prognostic and predictive testing in uveal melanoma The G protein α chaperone Ric-8 as a potential therapeutic target Melanoma: new insights and new therapies Adjuvant Therapy of Uveal Melanoma: Current Status Pathways and therapeutic targets in melanoma Emerging patterns of somatic mutations in cancer Resistance to BRAF inhibitors: unraveling mechanisms and future treatment options Melanoma: from mutations to medicine Metastatic uveal melanoma: biology and emerging treatments Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial.Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy Whole-genome sequencing reveals complex mechanisms of intrinsic resistance to BRAF inhibition.Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.TERT promoter mutation status as an independent prognostic factor in cutaneous melanoma.BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells.Clinical application of genetic testing for posterior uveal melanoma Metabolic rewiring in melanoma The genetics of uveal melanoma: current insights Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis Genetics of melanocytic nevi ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

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Mutations in GNA11 in uveal melanoma

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2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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Mutations in GNA11 in uveal melanoma

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The New England Journal of Medicine

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Mutations in GNA11 in uveal melanoma

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Adriana Heguy

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Gail Baimukanova

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Gary Green

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Joan O'Brien

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Klaus Busam

http://www.w3.org/2001/XMLSchema#string

M Mert Sozen

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Maria C Garrido

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Michelle B Crosby

http://www.w3.org/2001/XMLSchema#string

Nancy Bouvier

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Raya Khanin

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A comprehensive catalogue of somatic mutations from a human cancer genome

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

Oncogenic mutations in GNAQ occur early in uveal melanoma

GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4

Mutations of the BRAF gene in human cancer

G protein pathways.

Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants

Two G protein oncogenes in human endocrine tumors

Effects of G-protein mutations on skin color

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.

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2191-9

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scholarly article

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448330

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10.1056/NEJMOA1000584

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23

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363

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Michael R. Speicher

Boris C. Bastian

Catherine D Van Raamsdonk

Werner Wackernagel

Klaus G Griewank

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2010-12-02T00:00:00Z

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21083380

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3107972

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