Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes
about
Structural insights into bacterial resistance to ceruleninStructural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestisNetwork signatures link hepatic effects of anti-diabetic interventions with systemic disease parametersMuscle lipogenesis balances insulin sensitivity and strength through calcium signaling.Hepatic estrogen receptor α is critical for regulation of gluconeogenesis and lipid metabolism in males4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial functionMechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.Supplementation of persimmon leaf ameliorates hyperglycemia, dyslipidemia and hepatic fat accumulation in type 2 diabetic mice.Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.New Dietary Supplements for Obesity: What We Currently Know.Sphingolipid metabolism regulates development and lifespan in Caenorhabditis elegans.How lipidomics provides new insight into drug discovery.Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.Anti-obesity activity of the marine carotenoid fucoxanthin.De novo lipogenesis in metabolic homeostasis: More friend than foe?Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in miceFatty acid synthase and liver triglyceride metabolism: housekeeper or messenger?Ethanol Extract of Persimmon Tree Leaves Improves Blood Circulation and Lipid Metabolism in Rats Fed a High-Fat DietTiter improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026.Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029.A comprehensive review of glycosylated bacterial natural products.A Mutasynthetic Library of Platensimycin and Platencin Analogues.The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and MonkeysPlatensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.Biosynthetic Origin of the Ether Ring in Platensimycin.In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin.A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis.A Facile Semi-Synthetic Approach towards Halogen-Substituted Aminobenzoic Acid Analogues of Platensimycin.Antiinfectives targeting enzymes and the proton motive force.Global profiling strategies for mapping dysregulated metabolic pathways in cancer.Molecular and metabolic mechanisms of cardiac dysfunction in diabetes.Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis.De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health.The use of platensimycin and platencin to fight antibiotic resistance.Is diabetic cardiomyopathy a specific entity?Antidiabetic, Lipid Normalizing, and Nephroprotective Actions of the Strawberry: A Potent Supplementary Fruit.MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN.Modified SJH alleviates FFAs-induced hepatic steatosis through leptin signaling pathways.Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid.
P2860
Q27689556-AD29861F-BDB0-42AA-9234-A5748B11C50AQ28268619-EA42F3AA-F7C3-41FA-A593-5850FD613C43Q28652238-BE113753-A53D-4B0A-B4D3-6E8E556FB8A9Q30536570-EDC80AA2-7506-415E-A61D-C17435228012Q33687175-5EEF63C3-AACC-49D8-BAC2-361237E5EA11Q33761344-A719C2D2-5123-4C16-80B8-D81CF0202052Q34406049-774B3C31-7224-4116-A1C4-3CCC92310E0BQ34473894-CB5A7F00-3BD4-4822-99FE-0DE23EC3A48DQ34479743-1FC41493-BF39-46F6-AAF0-71877D56FFF8Q34521126-B0BE4070-6082-4187-9300-B9EBD9631EBFQ34938909-72619F12-FDFA-4232-B7D5-7334EFC9B367Q35167171-2A052CC6-E871-4B65-8874-E52FE1A675F8Q35170957-3DE68AF8-0197-4727-B826-F48DB2417E44Q35548885-AD03A004-6E81-4E0A-82AA-58235D84D194Q35573584-508C973D-4C49-43CC-BDDB-1941F50CAE3DQ35622450-5FF13A7E-C1B8-47B7-AB8D-5033E5021A1FQ35784513-22637D53-A537-4B8B-863D-FB4E4977AA52Q35821720-4880D415-D44C-4397-9DEA-D688BF671846Q36002415-D5D8ED3D-9ABF-4B23-BE20-541C485F2F27Q36004741-A86BE359-A43E-4626-BACB-08E396FBF04DQ36029831-7B56492C-D8FC-4ABF-9D1F-70FFB88E03BAQ36124142-EB112691-FE88-4F2E-9A5A-995CE4448D7BQ36151024-B0313F81-43CD-407F-AA9C-A6B500B308ECQ36198580-99416D97-2EC3-420F-8EB3-0DA680060C8AQ36223066-DF676F74-814C-43B3-81B1-72F5CF29B122Q36290806-7943DFAF-83BE-4CFE-8159-C0124C7DCD87Q36352736-1ED55966-75BA-4102-A48D-4F4CB985694AQ36408584-3EBD8C68-1C7F-411E-9958-BB639971CC6DQ36419761-3B9A19A5-AEAA-42D9-9FF6-904904356509Q36516956-0332DA8B-8EBC-4659-9846-D6CDF7CBB6A7Q36674142-8FA2E053-7738-4093-9FA9-0C2CFA8C1B30Q37076334-638D5251-E239-4953-B4DD-DEDD10ED5EF3Q37088326-0268B927-1F24-417E-ABA2-C4329180A689Q37203095-8019EB64-F1AB-4E83-9F3D-67B82949CE3EQ37575998-EDD0FB08-74CD-4593-AF8B-834F172C55B0Q37631570-FD92B32C-E3BC-4CF9-8807-CEBF6A7C784DQ37706642-E81F7AD5-E74B-470B-93EC-D0487D3F68D1Q37727871-704ACF4A-F610-4FA1-9765-73DC1E8D5D79Q38019608-6669D0A4-B63E-4B9C-BC57-F0A0C3A69E46Q38431516-80DCAC8C-2EC4-4615-8319-27AA5864C212
P2860
Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@ast
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@en
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@nl
type
label
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@ast
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@en
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@nl
prefLabel
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@ast
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@en
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@nl
P2093
P2860
P3181
P356
P1476
Antidiabetic and antisteatotic ...... in in mouse models of diabetes
@en
P2093
Bei B Zhang
Bindhu V Karanam
Christine C Chung
Corey Miller
Gino Salituro
Kenneth P Ellsworth
Margaret Wu
Maryann Powles
P2860
P304
P3181
P356
10.1073/PNAS.1002588108
P407
P577
2011-03-29T00:00:00Z