Ion access pathway to the transmembrane pore in P2X receptor channels - Test2 - elhamkhani - TriplyDB

Ion access pathway to the transmembrane pore in P2X receptor channels

Ion access pathway to the transmembrane pore in P2X receptor channels

http://www.wikidata.org/entity/Q24629121

about

Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1 Molecular and functional properties of P2X receptors--recent progress and persisting challenges Insights into the channel gating of P2X receptors from structures, dynamics and small molecules Size matters in activation/inhibition of ligand-gated ion channels Principles and properties of ion flow in P2X receptors Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms Molecular mechanism of ATP binding and ion channel activation in P2X receptors X-ray structures define human P2X3 receptor gating cycle and antagonist action Conductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane region Neuromodulation by extracellular ATP and P2X receptors in the CNS.Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor.Functional identification of close proximity amino acid side chains within the transmembrane-spanning helixes of the P2X2 receptor Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors).Role of domain calcium in purinergic P2X2 receptor channel desensitization Roles of the lateral fenestration residues of the P2X₄ receptor that contribute to the channel function and the deactivation effect of ivermectin Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals Gating mechanism of a P2X4 receptor developed from normal mode analysis and molecular dynamics simulations Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel.Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules.High potency zinc modulation of human P2X2 receptors and low potency zinc modulation of rat P2X2 receptors share a common molecular mechanism Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels.Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating.Insight into DEG/ENaC channel gating from genetics and structure.Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels.Post-translational regulation of P2X receptor channels: modulation by phospholipids Calcium-permeable ion channels in pain signaling.Heteromeric assembly of P2X subunits.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Ectodomain movements of an ATP-gated ion channel (P2X2 receptor) probed by disulfide locking.Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating P2X receptors The nervous system of airways and its remodeling in inflammatory lung diseases.P2X Receptor Activation.Inter-subunit disulfide locking of the human P2X3 receptor elucidates ectodomain movements associated with channel gating Direct gating of ATP-activated ion channels (P2X2 receptors) by lipophilic attachment at the outer end of the second transmembrane domain Mass spectrometry analysis of human P2X1 receptors; insight into phosphorylation, modelling and conformational changes.P2X4 Receptor in Silico and Electrophysiological Approaches Reveal Insights of Ivermectin and Zinc Allosteric Modulation.

P2860

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P2860

Ion access pathway to the transmembrane pore in P2X receptor channels

http://www.wikidata.org/entity/Q24629121

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Ion access pathway to the transmembrane pore in P2X receptor channels

@ast

Ion access pathway to the transmembrane pore in P2X receptor channels

@en

Ion access pathway to the transmembrane pore in P2X receptor channels

@nl

type

label

Ion access pathway to the transmembrane pore in P2X receptor channels

@ast

Ion access pathway to the transmembrane pore in P2X receptor channels

@en

Ion access pathway to the transmembrane pore in P2X receptor channels

@nl

prefLabel

Ion access pathway to the transmembrane pore in P2X receptor channels

@ast

Ion access pathway to the transmembrane pore in P2X receptor channels

@en

Ion access pathway to the transmembrane pore in P2X receptor channels

@nl

P1433

Q24629121-FC5FDA1A-15BE-4C9B-B13B-7024211DED16

P1476

Q24629121-03609E26-AF26-4312-B03D-D38DA3767FFF

P2093

Q24629121-37AB8074-514B-4750-8F54-63CE73A98F3E

Q24629121-6C5E0D3C-21BD-4B0A-9AE2-E9D01AD9A7D8

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P2860

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Q24629121-0E4246B0-935C-405F-A788-328E8840FA4B

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P304

Q24629121-52B8C624-C18C-429A-BBE1-9BBE6F79F73E

P31

Q24629121-9F5DB14D-8168-4791-8948-2DA937953ECC

P356

Q24629121-71AF601A-7941-45D3-9535-6851DC25D1DE

P407

Q24629121-881C92DD-36CA-4669-9804-9D2A265EDB4D

P433

Q24629121-48CB3147-3DBF-43D7-8C3E-6C3233803A67

P478

Q24629121-3A7BE325-834E-4DC7-864A-0247001C343E

P577

Q24629121-86C7DD3D-E9A7-4871-BC4E-DD17875602F4

P5875

Q24629121-948D6385-B90D-484C-B3E7-E1222DEB5BB2

P698

Q24629121-927B7BDC-165B-47DB-8044-51C11271FD9A

P921

Q24629121-7EC8DA67-13C1-48A4-88D4-216E3BA18DCA

P932

Q24629121-FAF219F0-764B-4C87-A321-11ACB74415E1

P356

P1433

The Journal of General Physiology

P1476

Ion access pathway to the transmembrane pore in P2X receptor channels

@en

P2093

Janice L Robertson

http://www.w3.org/2001/XMLSchema#string

Kenton J Swartz

http://www.w3.org/2001/XMLSchema#string

Mufeng Li

http://www.w3.org/2001/XMLSchema#string

Shai D Silberberg

http://www.w3.org/2001/XMLSchema#string

Toshimitsu Kawate

http://www.w3.org/2001/XMLSchema#string

P2860

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels.

Electrostatics of nanosystems: application to microtubules and the ribosome

Crystal structure of the ATP-gated P2X(4) ion channel in the closed state

CHARMM: the biomolecular simulation program

Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 A Resolution

Crystal structure of a Kir3.1-prokaryotic Kir channel chimera

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

Structure of the connexin 26 gap junction channel at 3.5 A resolution

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

P304

579-90

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1085/JGP.201010593

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

137

http://www.w3.org/2001/XMLSchema#string

P577

2011-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51177028

http://www.w3.org/2001/XMLSchema#string

P698

21624948

http://www.w3.org/2001/XMLSchema#string

P921

transmembrane protein

P932

3105519

http://www.w3.org/2001/XMLSchema#string