Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels.
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Insights into the channel gating of P2X receptors from structures, dynamics and small moleculesASICs as therapeutic targets for migraineX-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective ChannelCryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorinProtons and Psalmotoxin-1 reveal nonproton ligand stimulatory sites in chicken acid-sensing ion channel: Implication for simultaneous modulation in ASICs.General rules for the arrangements and gating motions of pore-lining helices in homomeric ion channels.Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors.Optical control of trimeric P2X receptors and acid-sensing ion channelsFunctional architecture of the CFTR chloride channel.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Structural Changes Fundamental to Gating of the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Pore.P2X receptorsPseudohypoaldosteronism type 1 and Liddle's syndrome mutations that affect the single-channel properties of the epithelial Na+ channel.Interaction of Purinergic P2X4 and P2X7 Receptor Subunits.Intersubunit physical couplings fostered by the left flipper domain facilitate channel opening of P2X4 receptors.The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel.Allosteric modulation as a unifying mechanism for receptor function and regulation.
P2860
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P2860
Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels.
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article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Unanticipated parallels in arc ...... and acid sensing ion channels.
@en
type
label
Unanticipated parallels in arc ...... and acid sensing ion channels.
@en
prefLabel
Unanticipated parallels in arc ...... and acid sensing ion channels.
@en
P2093
P2860
P1476
Unanticipated parallels in arc ...... and acid sensing ion channels.
@en
P2093
Eric Gouaux
Isabelle Baconguis
Motoyuki Hattori
P2860
P304
P356
10.1016/J.SBI.2013.04.005
P577
2013-04-26T00:00:00Z